Understanding COVID-19 pandemic: molecular mechanisms and potential therapeutic strategies. An evidence-based review

R Hanna, S Dalvi, T Sălăgean, ID Pop… - Journal of …, 2021 - Taylor & Francis
Abstract Initially, the SARS-CoV-2 virus was considered as a pneumonia virus; however, a
series of peer reviewed medical papers published in the last eight months suggest that this …

An updated insight into the molecular pathogenesis, secondary complications and potential therapeutics of COVID-19 pandemic

S Jamwal, A Gautam, J Elsworth, M Kumar, R Chawla… - Life sciences, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is an unprecedented disease caused by
highly pathogenic SARS-CoV-2 and characterized by extreme respiratory deterrence …

[HTML][HTML] SARS-CoV-2: From structure to pathology, host immune response and therapeutic management

G Mihaescu, MC Chifiriuc, C Iliescu, CO Vrancianu… - Microorganisms, 2020 - mdpi.com
Coronaviruses are large, enveloped viruses with a single-stranded RNA genome, infecting
both humans and a wide range of wild and domestic animals. SARS-CoV-2, the agent of the …

The emergence of COVID-19 as a global pandemic: Understanding the epidemiology, immune response and potential therapeutic targets of SARS-CoV-2

S Muralidar, SV Ambi, S Sekaran, UM Krishnan - Biochimie, 2020 - Elsevier
An acute respiratory disease caused by a severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) that surfaced in China in late 2019, continues to spread rapidly across the …

[HTML][HTML] A brief overview of SARS-CoV-2 infection and its management strategies: a recent update

A Das, S Pathak, M Premkumar… - Molecular and Cellular …, 2023 - Springer
The COVID-19 pandemic has become a global health crisis, inflicting substantial morbidity
and mortality worldwide. A diverse range of symptoms, including fever, cough, dyspnea, and …

[HTML][HTML] Recent advances in pathophysiology, drug development and future perspectives of SARS-CoV-2

DD Singh, I Han, EH Choi, DK Yadav - Frontiers in cell and …, 2020 - frontiersin.org
The coronavirus (SARS-CoV-2) pandemic is a rapidly transmitting and highly pathogenic
disease. The spike protein of SARS-CoV-2 binds to the surface of angiotensin-converting …

[HTML][HTML] Molecular perspectives of SARS-CoV-2: pathology, immune evasion, and therapeutic interventions

M Shah, HG Woo - Molecules and Cells, 2021 - Elsevier
The outbreak of coronavirus disease 2019 (COVID-19) has not only affected human health
but also diverted the focus of research and derailed the world economy over the past year …

[HTML][HTML] COVID-19: a global challenge with old history, epidemiology and progress so far

M Khan, SF Adil, HZ Alkhathlan, MN Tahir, S Saif… - Molecules, 2020 - mdpi.com
Humans have witnessed three deadly pandemics so far in the twenty-first century which are
associated with novel coronaviruses: SARS, Middle East respiratory syndrome (MERS), and …

[HTML][HTML] An update to “novel therapeutic approaches for treatment of COVID-19”

N Hossein-Khannazer, B Shokoohian… - Journal of Molecular …, 2021 - Springer
Although the exact mechanism of pathogenesis in COVID-19 is not fully understood,
cytokine storm following viral infection plays an important role in the initiation and …

[HTML][HTML] Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets

M Farahani, Z Niknam, LM Amirabad… - Biomedicine & …, 2022 - Elsevier
Deciphering the molecular downstream consequences of severe acute respiratory
syndrome coronavirus (SARS-CoV)− 2 infection is important for a greater understanding of …