Pharmacologically inhibiting nucleotide-binding domain and leucine-rich repeat-containing
(NLR) family, pyrin domain–containing protein 3 (NLRP3) inflammasome activation results …

The nucleotide-binding-domain (NBD)–and leucine-rich repeat (LRR)–containing (NLR)
family, pyrin-domain–containing 3 (NLRP3) inflammasome drives pathological inflammation …

The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is a multi-
protein complex that can be activated by a variety of pathogen-associated molecular …

NLRP3 (NOD-, LRR-, and pyrin domain-containing protein 3) is a cytosolic pattern
recognition receptor (PRR) that recognizes multiple pathogen-associated molecular patterns …

The NLRP3 inflammasome has been implicated in the pathogenesis of a wide variety of
human diseases. A few compounds have been developed to inhibit NLRP3 inflammasome …

Intracellular sensing of stress and danger signals initiates inflammatory innate immune
responses by triggering inflammasome assembly, caspase-1 activation and pyroptotic cell …

The cytosolic pattern recognition receptor (PRR) NOD-like receptor family, pyrin domain
containing 3 (NLRP3) senses a wide range of pathogen-associated molecular patterns …

Abstract The NACHT, LRR, and PYD domains‐containing protein 3 (NLRP3) inflammasome
is a multimolecular complex that plays a fundamental role in inflammation. Optimal activation …

The protein NLRP3 has emerged as a central regulator in the inflammatory process, being
implicated directly in hereditary cryopyrinopathies, and indirectly in diseases such as gout …

The dysregulation of NLRP 3 inflammasome can cause uncontrolled inflammation and drive
the development of a wide variety of human diseases, but the medications targeting NLRP 3 …