Cardiotoxicity of anticancer drugs: Molecular mechanisms and strategies for cardioprotection

MB Morelli, C Bongiovanni, S Da Pra… - Frontiers in …, 2022 - frontiersin.org
Chemotherapy and targeted therapies have significantly improved the prognosis of
oncology patients. However, these antineoplastic treatments may also induce adverse …

Anticancer drugs and cardiotoxicity: insights and perspectives in the era of targeted therapy

E Raschi, V Vasina, MG Ursino, G Boriani… - Pharmacology & …, 2010 - Elsevier
Drug-induced cardiotoxicity is emerging as an important issue among cancer survivors. For
several decades, this topic was almost exclusively associated with anthracyclines, for which …

Cardiotoxicity of anticancer therapeutics

J Dong, H Chen - Frontiers in cardiovascular medicine, 2018 - frontiersin.org
As cancer therapeutics continues to improve and progress, the adverse side effects
associated with anticancer treatments have also attracted more attention and have become …

Mechanisms of cardiotoxicity of cancer chemotherapeutic agents: cardiomyopathy and beyond

R Moudgil, ETH Yeh - Canadian Journal of Cardiology, 2016 - Elsevier
Tremendous strides have been made in the treatment of various oncological diseases such
that patients are surviving longer and are having better quality of life. However, the success …

Cardiotoxic effects of chemotherapy: A review of both cytotoxic and molecular targeted oncology therapies and their effect on the cardiovascular system

HM Babiker, A McBride, M Newton, LM Boehmer… - Critical reviews in …, 2018 - Elsevier
Cardiotoxic effects of chemotherapy and targeted drugs are ubiquitous and challenging in
the field of oncology therapeutics. The broad spectrum of toxicities ranging from ischemic …

Breakthroughs in modern cancer therapy and elusive cardiotoxicity: Critical research‐practice gaps, challenges, and insights

PP Zheng, J Li, JM Kros - Medicinal research reviews, 2018 - Wiley Online Library
To date, five cancer treatment modalities have been defined. The three traditional modalities
of cancer treatment are surgery, radiotherapy, and conventional chemotherapy, and the two …

Preclinical models of cancer therapy–associated cardiovascular toxicity: a scientific statement from the American heart association

A Asnani, JJ Moslehi, BB Adhikari, AH Baik… - Circulation …, 2021 - Am Heart Assoc
Although cardiovascular toxicity from traditional chemotherapies has been well recognized
for decades, the recent explosion of effective novel targeted cancer therapies with …

Cardiotoxicity

I Braña, E Zamora, J Tabernero - Side Effects of Medical Cancer Therapy …, 2013 - Springer
Although outcomes in cancer patients have dramatically improved with the development of
novel cancer chemotherapies and combination treatment, these developments are …

Curing cancer, saving the heart: a challenge that cardioncology should not miss

D Cardinale, G Biasillo, CM Cipolla - Current cardiology reports, 2016 - Springer
Advances in oncologic therapies have led to considerable improvements in prognosis and
survival. However, these improvements may ultimately be diminished by the increase of …

Cardioprotective strategies from cardiotoxicity in cancer patients: a comprehensive review

C Kourek, M Touloupaki, A Rempakos, K Loritis… - Journal of …, 2022 - mdpi.com
Cardiotoxicity is a significant complication of chemotherapeutic agents in cancer patients.
Cardiovascular incidents including LV dysfunction, heart failure (HF), severe arrhythmias …