ZnBr 2-Mediated oxidative spiro-bromocyclization of propiolamide for the synthesis of 3-bromo-1-azaspiro [4.5] deca-3, 6, 9-triene-2, 8-dione

Y He, G Qiu - Organic & Biomolecular Chemistry, 2017 - pubs.rsc.org
ZnBr2-Mediated oxidative spiro-bromocyclization of N-arylpropiolamide has been described
herein for the synthesis of 3-bromo-1-azaspiro [4.5] deca-3, 6, 9-triene-2, 8-dione with high …

Photomediated Spirocyclization of N-Benzyl Propiolamide with N-Iodosuccinimide for Access to Azaspiro[4.5]deca-6,9-diene-3,8-dione

M Yang, J Hua, H Wang, T Ma, C Liu… - The Journal of …, 2022 - ACS Publications
A metal-and oxidant-free route for affording azaspiro [4.5] deca-6, 9-diene-3, 8-dione via
photomediated iodinated spirocyclization of N-(4-methoxybenzyl) propiolamide has been …

Ortho-Hydroxylative ipso-Cyclization of N-arylpropiolamide

YC Wang, JB Liu, H Zhou, W Xie… - The Journal of …, 2019 - ACS Publications
A facile protocol for the tunable synthesis of 10-hydroxy-1-azaspiro [4.5] deca-3, 6, 8-trien-2-
ones and benzo [b] pyrrolo [2, 1-c][1, 4] oxazin-3-ones is described. A tunable synthesis has …

[HTML][HTML] Synthesis of sulfur-containing benzo [b] pyrrolo [2, 1-c][1, 4] oxazine-3, 9-diones: blue light promoted radical cyclization process

F Pan, H Li, X Wang, L Luo, Y Lin, Q Yu, W Xie… - RSC …, 2023 - pubs.rsc.org
The selective and controllable construction of spio-tricyclic skeletons through visible light
promoted radical cyclization still remains challenging. Herein, a general and convenient …

N,N,N′,N′‐Tetramethylchloroformamidinium Chloride‐Mediated Cyclizations of β‐Oxo Amides: Facile and Divergent One‐Pot Synthesis of Substituted 2H‐Pyrans, 4H …

Y Wang, X Xin, Y Liang, Y Lin, H Duan… - Advanced Synthesis & …, 2009 - Wiley Online Library
An efficient and divergent one‐pot synthesis of substituted 2H‐pyrans, 4H‐pyrans and
pyridin‐2 (1H)‐ones from β‐oxo amides based on the selection of the reaction conditions is …

Metal‐free Synthesis of Spiro‐2,2′‐benzo[b]furan‐3,3′‐ones via PhI(OAc)2‐Mediated Cascade Spirocyclization

Q Xing, H Liang, M Bao, X Li, J Zhang… - Advanced Synthesis …, 2019 - Wiley Online Library
Treating the benzyl protected 3‐hydroxy‐1, 3‐bis (2‐hydroxyphenyl) prop‐2‐en‐1‐ones
solely with PhI (OAc) 2 (PIDA) in DCE at room temperature readily furnished the seldom …

TBAI-mediated regioselective 5-exo-dig iodinative oxocyclization of 2-alkynylbenzamides for the synthesis of isobenzofuran-1-imines and isobenzofurans

YH Wang, JB Liu, B Ouyang, H Zhou, G Qiu - Tetrahedron, 2018 - Elsevier
Alkyne-based regioselective functionalization is an important transformation method for the
synthesis of a wide variety of organic products. In this work, a regioselective TBAI-mediated …

Controllable Synthesis of N- and O-Containing Heterocycles via Formal [3 + 2] and [5 + 2] Cyclizations

Z Sun, R Hou, SS Li, X Wang, L Wang, F Hu… - Organic …, 2023 - ACS Publications
The controllable synthesis of spirooxindole–dihydrofurans and spirooxindole–benzazepines
was developed through formal [3+ 2] and [5+ 2] cyclization reactions from 2-(2-oxoindolin-3 …

TBAB-mediated radical 6-endo-trig ortho-cyclization of N-aryl-N-(prop-2-yn-1-yl) benzenesulfonamide for the synthesis of 3-bromo-1, 2-dihydroquinoline

M Yang, X Hu, B Ouyang, W Xie, JB Liu - Tetrahedron, 2019 - Elsevier
In this work, we described a new synthetic route of 3-bromo-1, 2-dihydroquinoline
derivatives based on the TBAB/Oxone-mediated radical 6-endo-trig ortho-cyclization of 2 …

TBAB‐Mediated Radical 5‐exo‐trig ipso‐Cyclization of 2‐Arylbenzamide for the Synthesis of Spiro[cyclohexane‐1,1′‐isoindoline]‐2,5‐diene‐3′,4‐dione

G Qiu, ZF Chen, W Xie, H Zhou - European Journal of Organic …, 2019 - Wiley Online Library
A TBAB‐mediated radical 5‐exo‐trig ipso‐cyclization of N‐aryl‐2‐arylbenzamide is
described herein for the synthesis of spiro [cyclohexane‐1, 1′‐isoindoline]‐2, 5‐diene‐3 …