Introduction: Straightforward studies compared adeno-associated virus (AAV) serotypes to
determine the most appropriate one for robust expression in the CNS. AAV9 was efficient …

Recombinant adeno-associated viral (AAV) vectors can transduce cells of the CNS, resulting
in long-term expression. AAV vector transduction varies depending on the serotype used …

Delivering genes to and across the brain vasculature efficiently and specifically across
species remains a critical challenge for addressing neurological diseases. We have evolved …

We examined the transduction efficiency of different adeno-associated virus (AAV) capsid
serotypes encoding for green fluorescent protein (GFP) flanked by AAV2 inverted terminal …

Recombinant Adeno-associated virus vectors (rAAV) are widely used for gene delivery and
multiple naturally occurring serotypes have been harnessed to target cells in different …

Adeno-associated virus (AAV) vector, an excellent gene therapy vector, has been widely
used in the treatment of various central nervous system (CNS) diseases. Due to the …

Adeno-associated virus (AAV) capsid libraries have generated improved transgene delivery
vectors. We designed an AAV library construct, iTransduce, that combines a peptide library …

Adeno-associated virus (AAV) vectors exhibit a number of properties that have made this
vector system an excellent choice for both CNS gene therapy and basic neurobiological …

Adeno-associated virus (AAV) vectors are showing promise in gene therapy trials and have
proven to be extremely efficient biological tools in basic neuroscience research. One major …

Adeno-associated virus (AAV) mediated gene expression is a powerful tool for gene therapy
and preclinical studies. A comprehensive analysis of CNS cell type tropism, expression …