Following injury to the central nervous system (CNS) there is a cascade of events that leads
to cell death, tissue loss and consequently functional deficit. In response to injury, the CNS …

Stem cell therapies have the potential to not only repair, but to regenerate tissue of the
central nervous system (CNS). Recent studies demonstrate that transplanted stem cells can …

Ongoing clinical trials are evaluating the use of stem cells as a way to treat traumatic spinal
cord injury (SCI). However, the inhibitory environment present in the injured spinal cord …

Traumatic injury to the central nervous system (CNS) is highly debilitating, with the clinical
need for regenerative therapies apparent. Neural stem/progenitor cells (NSPCs) are …

The health of the central nervous system (CNS) does not only rely on the state of the neural
cells but also on how various extracellular components organize cellular behaviors into …

Permanent deficits that occur in memory, sensation, and cognition can result from central
nervous system (CNS) trauma that causes dysfunction and/or unregulated CNS …

Transplantation of stem cells is a promising potential therapy for central nervous system
disease and injury. The capacity for self-renewal, proliferation of progenitor cells, and multi …

The central nervous system (CNS) has a limited capacity to spontaneously regenerate
following traumatic injury or disease, requiring innovative strategies to promote tissue and …

Nerve injuries can be life-long debilitating traumas that severely impact patients' quality of
life. While many acellular neural scaffolds have been developed to aid the process of nerve …

Biomaterials are likely to have an increasingly important role in the treatment of nervous
system disorders. Recently developed biomaterials can enable and augment the targeted …