Identification of unique immune response expression profiles to SARS-CoV-2 in non-small cell lung cancer using systems immunology approach

S Al Heialy, MY Hachim, IY Hachim… - … in Biomedical and …, 2022 - journals.lww.com
Background: COVID-19 severity and mortality are higher in patients with lung cancer due to
pulmonary complications. Understanding the mechanisms of SARS-COV-2 effect on lung …

Risk factors and actionable molecular signatures in COVID-19-associated lung adenocarcinoma and lung squamous cell carcinoma patients

MA Ullah, S Alam, AT Moin, T Ahamed… - Computers in Biology …, 2023 - Elsevier
The molecular mechanism of the pathological impact of COVID-19 in lung cancer patients
remains poorly understood to date. In this study, we used differential gene expression …

[HTML][HTML] Identification and classification of differentially expressed genes reveal potential molecular signature associated with SARS-CoV-2 infection in lung …

OS Soremekun, KF Omolabi, MES Soliman - Informatics in medicine …, 2020 - Elsevier
Genomic techniques such as next-generation sequencing and microarrays have facilitated
the identification and classification of molecular signatures inherent in cells upon viral …

[HTML][HTML] Computational identification and experimental verification of a novel signature based on SARS-CoV-2–related genes for predicting prognosis, immune …

Y Wang, Y Xu, Y Deng, L Yang, D Wang… - Frontiers in …, 2024 - frontiersin.org
Background Early research indicates that cancer patients are more vulnerable to adverse
outcomes and mortality when infected with severe acute respiratory syndrome coronavirus 2 …

Transcriptional profiles and common genes link lung cancer with the development and severity of COVID-19

SS Cury, JS Oliveira, CAO Biagi-Júnior, WA Silva Jr… - Gene, 2023 - Elsevier
Lung cancer patients with COVID-19 present an increased risk of developing severe
disease and, consequently, have poor outcomes. Determining SARS-CoV-2-host …

[HTML][HTML] Perspective on the treatment of non-small cell lung cancer in the context of potential SARS-CoV-2 infection during the pandemic

G Theodoropoulos, K Albanis… - Journal of current …, 2021 - ncbi.nlm.nih.gov
SARS-CoV-2 infections are rising at an alarming rate and various aspects of this pandemic
must be quickly and adequately addressed in order to enhance effective healthcare delivery …

229P Identify the impact of SARS-CoV-2 on lung cancer tumorigenesis using host-pathogen interaction network analysis

R Kumar - Immuno-Oncology and Technology, 2022 - esmoiotech.org
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the
coronavirus variant that started the global pandemic and infected more than 12 million …

Identifying potential gene defect patterns related to COVID-19 based on pharmacological and bioinformatics analysis for lung adenocarcinoma

H Lou, X Li, S Gao, Y Zhang, H Chen… - International journal of …, 2022 - Taylor & Francis
Abstract Background Coronavirus disease 2019 (COVID-19) greatly affects cancer patients,
especially those with lung cancer. This study aimed to identify potential drug targets for lung …

Prediction of SARS-CoV-2 Infection Phosphorylation Sites and Associations of these Modifications with Lung Cancer Development

W Li, G Li, Y Sun, L Zhang, X Cui, Y Jia… - Current Gene …, 2024 - ingentaconnect.com
Introduction: Since the emergence of SARS-CoV-2 viruses, multiple mutant strains have
been identified. Infection with SARS-CoV-2 virus leads to alterations in host cell …

How does SARS‐CoV‐2 infection impact on immunity, procession and treatment of pan cancers

N Xiong, Q Sun - Journal of Medical Virology, 2023 - Wiley Online Library
We identified 14 immune‐related differentially Expressed Genes (DEGs) between COVID‐
19 patients and normal controls and the receiver operator characteristic curve results …