A multi-omics investigation of the composition and function of extracellular vesicles along the temporal trajectory of COVID-19

SM Lam, C Zhang, Z Wang, Z Ni, S Zhang, S Yang… - Nature …, 2021 - nature.com
Exosomes represent a subtype of extracellular vesicle that is released through retrograde
transport and fusion of multivesicular bodies with the plasma membrane. Although no …

[PDF][PDF] Omics-driven systems interrogation of metabolic dysregulation in COVID-19 pathogenesis

JW Song, SM Lam, X Fan, WJ Cao, SY Wang, H Tian… - Cell metabolism, 2020 - cell.com
Summary The coronavirus disease 2019 (COVID-19) pandemic presents an unprecedented
threat to global public health. Herein, we utilized a combination of targeted and untargeted …

[HTML][HTML] Circulating exosomes are strongly involved in SARS-CoV-2 infection

E Barberis, VV Vanella, M Falasca… - Frontiers in molecular …, 2021 - frontiersin.org
Knowledge of the host response to the novel coronavirus SARS-CoV-2 remains limited,
hindering the understanding of COVID-19 pathogenesis and the development of therapeutic …

Multifunctional role of exosomes in viral diseases: From transmission to diagnosis and therapy

P Chaudhari, V Ghate, M Nampoothiri, S Lewis - Cellular signalling, 2022 - Elsevier
Efforts to discover antiviral drugs and diagnostic platforms have intensified to an
unprecedented level since the outbreak of COVID-19. Nano-sized endosomal vesicles …

The role of extracellular vesicles in COVID-19 virus infection

M Hassanpour, J Rezaie, M Nouri, Y Panahi - Infection, Genetics and …, 2020 - Elsevier
Extracellular vesicles releasing from various types of cells contribute to intercellular
communication via delivering bio-molecules like nucleic acids, proteins, and lipids to …

Emerging roles of extracellular vesicles in COVID‐19, a double‐edged sword?

X Xia, P Yuan, Y Liu, Y Wang, W Cao, JC Zheng - Immunology, 2021 - Wiley Online Library
The sudden outbreak of SARS‐CoV‐2‐infected disease (COVID‐19), initiated from Wuhan,
China, has rapidly grown into a global pandemic. Emerging evidence has implicated …

[HTML][HTML] Diverse effects of exosomes on COVID-19: a perspective of progress from transmission to therapeutic developments

S Gurunathan, MH Kang, JH Kim - Frontiers in immunology, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new strain of
coronavirus and the causative agent of the current global pandemic of coronavirus disease …

[HTML][HTML] The potential role of extracellular vesicles in COVID-19 associated endothelial injury and pro-inflammation

B Krishnamachary, C Cook, L Spikes, P Chalise… - medRxiv, 2020 - ncbi.nlm.nih.gov
COVID-19 infection caused by the novel severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) has resulted in a global pandemic with the number of deaths growing …

COVID-19 and extracellular vesicles: an intriguing interplay

G Pocsfalvi, R Mammadova… - Kidney and Blood …, 2020 - karger.com
Background: The outbreak of severe acute respiratory syndrome β-coronavirus 2 (SARS-
CoV-2) has the potential to become a long-lasting global health crisis. The number of people …

Clinical applications for exosomes: Are we there yet?

D Perocheau, L Touramanidou… - British journal of …, 2021 - Wiley Online Library
Exosomes are a subset of extracellular vesicles essential for cell–cell communication in
health and disease with the ability to transport nucleic acids, functional proteins and other …