Structure of severe fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential

L Jiao, S Ouyang, M Liang, F Niu, N Shaw… - Journal of …, 2013 - Am Soc Microbiol
Severe fever with thrombocytopenia syndrome is an emerging infectious disease caused by
a novel bunyavirus (SFTSV). Lack of vaccines and inadequate therapeutic treatments have …

The nucleoprotein of severe fever with thrombocytopenia syndrome virus processes a stable hexameric ring to facilitate RNA encapsidation

H Zhou, Y Sun, Y Wang, M Liu, C Liu, W Wang… - Protein & …, 2013 - academic.oup.com
Severe fever with thrombocytopenia syndrome virus (SFTSV), a member of the Phlebovirus
genus from the Bunyaviridae family endemic to China, is the causative agent of life …

Non-structural protein-W61 as a novel target in severe fever with thrombocytopenia syndrome virus (SFTSV): an in-vitro and in-silico study on protein-protein …

JY Park, C Sivasankar, P Kirthika, D Prabhu, JH Lee - Viruses, 2023 - mdpi.com
The non-structural protein (NSs) and nucleoprotein (NP) of the severe fever with
thrombocytopenia syndrome virus (SFTSV) encoded by the S segment are crucial for viral …

Roles of viroplasm‐like structures formed by nonstructural protein NSs in infection with severe fever with thrombocytopenia syndrome virus

X Wu, X Qi, M Liang, C Li, CJ Cardona, D Li… - The FASEB …, 2014 - Wiley Online Library
Severe fever with thrombocytopenia syndrome (SFTS) virus is an emerging bunyavirus that
causes a hemorrhagic fever with a high mortality rate. The virus is likely tick‐borne and …

Structural and functional characterization of the severe fever with thrombocytopenia syndrome virus L protein

D Vogel, SR Thorkelsson, ERJ Quemin… - Nucleic acids …, 2020 - academic.oup.com
The Bunyavirales order contains several emerging viruses with high epidemic potential,
including Severe fever with thrombocytopenia syndrome virus (SFTSV). The lack of medical …

Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein

HM Williams, SR Thorkelsson, D Vogel… - Nucleic acids …, 2023 - academic.oup.com
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a phenuivirus that has
rapidly become endemic in several East Asian countries. The large (L) protein of SFTSV …

Architecture of severe fever with thrombocytopenia syndrome virus

Z Sun, J Cheng, Y Bai, L Cao, D Xie, F Deng… - Protein & …, 2023 - academic.oup.com
Severe fever with thrombocytopenia syndrome (SFTS) is an acute infectious disease caused
by severe fever with thrombocytopenia syndrome virus (SFTSV) and is characterized by …

Reverse genetics system for severe fever with thrombocytopenia syndrome virus

B Brennan, P Li, S Zhang, A Li, M Liang, D Li… - Journal of …, 2015 - Am Soc Microbiol
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne
pathogen that was first reported in China in 2009. Phylogenetic analysis of the viral genome …

A natural variation in the RNA polymerase of severe fever with thrombocytopenia syndrome virus enhances viral replication and in vivo virulence

K Jeon, HJ Ro, JG Kang, DE Jeong… - Journal of Medical …, 2023 - Wiley Online Library
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick‐borne disease
with high mortality in Eastern Asia. The disease is caused by the SFTS virus (SFTSV), also …

The Severe Fever with Thrombocytopenia Syndrome Virus NSs Protein Interacts with CDK1 To Induce G2 Cell Cycle Arrest and Positively Regulate Viral Replication

S Liu, H Liu, J Kang, L Xu, K Zhang, X Li… - Journal of …, 2020 - Am Soc Microbiol
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a newly identified
phlebovirus associated with severe hemorrhagic fever in humans. While many viruses …