Cytokine storm syndrome (CSS) is a critical clinical condition induced by a cascade of
cytokine activation, characterized by overwhelming systemic inflammation …

Although interest in “cytokine storms” has surged over the past decade, it was massively
amplified in 2020 when it was suggested that a subset of patients with COVID-19 developed …

In December 2019, a novel coronavirus, COVID-19, was discovered to be the causal agent
of a severe respiratory infection named SARS-CoV-2, and it has since been recognized …

Hyperinflammation is a key component of severe COVID-19, residing underneath the
cytokine storm umbrella term, associated with poor outcomes. Better understanding of the …

ABSTRACT SARS-CoV-2 has claimed 2,137,908 lives in more than a year. Some COVID-19
patients experience sudden and rapid deterioration with the onset of fatal cytokine storm …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak in Wuhan,
China has dispersed rapidly worldwide. Although most patients present with mild fever …

Abstract Coronavirus disease 2019 (COVID-19) outbreak has become a global public health
emergency and has led to devastating results. Mounting evidence proposes that the disease …

A cytokine storm is a hyperinflammatory state secondary to the excessive production of
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …

Cytokine storm is an acute hyperinflammatory response that may be responsible for critical
illness in many conditions including viral infections, cancer, sepsis, and multi-organ failure …

The COVID-19 pandemic has placed the practice of medicine at a threshold overlooking a
new and different era, 1 and has led to the evolving concept of COVID-19 cytokine storm …