Immunotherapy in COVID-19: why, who, and when?

P Sinha, CS Calfee - The Lancet Respiratory Medicine, 2021 - thelancet.com
Nearly 1· 5 years into the global COVID-19 pandemic, immense progress has been made
against SARS-CoV-2 in health care, most prominently in vaccine development. However …

The course of action for effective anti-cytokine treatment in COVID-19

G Cavalli, L Dagna - The Lancet Respiratory Medicine, 2021 - thelancet.com
Even in the aftermath of global anti-SARS-CoV-2 vaccination campaigns, safe and effective
treatments to inhibit inflammation and reduce mortality continue to be needed for the …

The right place for IL-1 inhibition in COVID-19

G Cavalli, L Dagna - The Lancet Respiratory Medicine, 2021 - thelancet.com
The COVID-19 pandemic, caused by the spread of severe acute respiratory syndrome
coronavirus 2, has resulted in more than 1· 8 million deaths worldwide as of Jan 7, 2021, a …

Immunomodulation in COVID-19

NE Ingraham, S Lotfi-Emran, BK Thielen… - The Lancet …, 2020 - thelancet.com
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome corona virus 2 (SARS-CoV-2), continues to spread globally despite …

Immunotherapies for COVID-19: lessons learned from sepsis

KE Remy, SC Brakenridge, B Francois… - The Lancet …, 2020 - thelancet.com
Therapeutic approaches to mitigate the severe acute lung injury associated with severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have rapidly entered …

[HTML][HTML] Intravenous immunoglobulin therapy for COVID-19 ARDS

EM Wilfong, MA Matthay - The Lancet Respiratory Medicine, 2022 - thelancet.com
To date, the SARS-CoV-2 virus and COVID-19 has killed more than 4 million individuals
worldwide. Morbidity and mortality arise from direct viral-induced injury to multiple organ …

[HTML][HTML] Waning immunity to SARS-CoV-2: implications for vaccine booster strategies

DM Altmann, RJ Boyton - The lancet respiratory medicine, 2021 - thelancet.com
As we approach the end of the second year of the COVID-19 pandemic, of the many
challenges facing immunologists and vaccinologists, one of the toughest has been the …

Early treatment to prevent progression of SARS-CoV-2 infection

MS Cohen - The Lancet Respiratory Medicine, 2022 - thelancet.com
As of May, 2022, the SARS-CoV-2 virus has caused 521 million COVID-19 cases and at
least 6 million deaths, worldwide. 1 Although the COVID-19 pandemic has led to …

[HTML][HTML] Battling COVID-19-related mortality: from a fight for ventilators to a cry for oxygen

MJ Schultz, AS Neto, F Paulus - The Lancet Respiratory Medicine, 2021 - thelancet.com
COVID-19 has caused hundreds of thousands of intensive care unit (ICU) admissions
worldwide, and this number continues to increase rapidly as of mid-May, 2021, particularly …

Monoclonals for patients hospitalised with COVID-19

JM Pogue, EK McCreary - The Lancet Respiratory Medicine, 2022 - thelancet.com
The Lancet Respiratory Medicine, Thomas L Holland and colleagues present results of the
ACTIV-3 trial comparing intravenous tixagevimab− cilgavimab with placebo for patients …