Therapeutic biologics such as genes, peptides, proteins, virus and cells provide clinical
benefits and are becoming increasingly important tools in respiratory medicine. Pulmonary …

Drugs for inhalation are no longer exclusively highly crystalline small molecules. They may
also be amorphous small molecules, peptides, antibodies, and myriad types of engineered …

The pulmonary route has long been used for drug administration for both local and systemic
treatment. It possesses several advantages, which can be categorized into physiological, ie …

Enhanced therapeutics are drug products derived from existing generic drugs that provide
additional benefits to the patients and the healthcare system. Enhanced therapeutics are …

This review examines the key issues surrounding the development and preparation of
formulations for dry powder inhalers. The various inhaler devices that are currently available …

Pulmonary drug delivery can have several advantages over other administration routes, in
particular when using dry powder formulations. Such dry powder inhalation formulations …

Pulmonary delivery of biopharmaceuticals may enable targeted local therapeutic effect and
noninvasive systemic administration. Dry powder inhaler (DPI) delivery is an established …

Introduction: Early dry powder inhalers (DPIs) were designed for low drug doses in asthma
and COPD therapy. Nearly all concepts contained carrier-based formulations and lacked …

Increasing prevalence of pulmonary diseases with high mortality and morbidity such as
chronic obstructive pulmonary disease (COPD), asthma, cystic fibrosis, infectious diseases …

In the last decades, dry powder inhalation has become a very attractive option for pulmonary
drug delivery to treat lung diseases like cystic fibroses and lung infections. In contrast to the …