Nanoparticles bring many benefits to pulmonary drug delivery applications, especially for
systemic delivery and drugs with poor solubility. They have recently been explored in …

Significant advances have been made in the last 50 years in developing safe and
efficacious aerosol formulations for pulmonary delivery. The key to future innovation may lie …

The growing interest on polymeric delivery systems for pulmonary administration of drugs
anticipates a more direct and efficient treatment of diseases such as tuberculosis (TB) that …

Spray-drying is a common practice of powder preparation for a wide range of drugs. Spray-
dried powders can be used to deliver particles to the lungs via a dry powder inhaler (DPI) …

Particle design for inhalation is characterized by advances in particle processing methods
and the utilization of new excipients. Processing methods such as spray drying allow control …

Purpose Inhalation of low-density porous particles enables deep lung delivery with less
dependence on device design and patient inspiration. The purpose of this study was to …

The lungs are an attractive route for non-invasive drug delivery with advantages for both
systemic and local applications. Incorporating therapeutics with polymeric nanoparticles …

Historically, pharmaceutical aerosols have been employed for the treatment of obstructive
airway diseases, such as asthma and chronic obstructive pulmonary disease, but in the past …

Compared with oral and parenteral formulations, inhaled formulations are attractive because
of their great benefit and potential to enhance therapeutic effects of medications. Among the …

The delivery of therapeutic proteins remains a challenge, despite recent technological
advances. While the delivery of proteins to the lungs is the gold standard for topical and …