Impediments to DNA access due to assembly of the eukaryotic genome into chromatin are in
part overcome by the activity of ATP‐dependent chromatin‐remodeling complexes. These …

The human ISWI-containing factor RSF (r emodeling and s pacing f actor) was found to
mediate nucleosome deposition and, in the presence of ATP, generate regularly spaced …

Chromatin remodeling ATPases are conserved across species from yeast to human and
much of what we know about their function, mechanism of action and regulation comes from …

We had recently characterized SLC, a SWI/SNF-like chromatin remodelling activity, from
chicken liver. The SLC efficiently disrupts nucleosomes, transfers histone octamers from …

Repressive chromatin structures need to be unravelled to allow DNA-binding proteins
access to their target sequences. This de-repression constitutes an important point at which …

The structure and function of the Saccharomyces cerevisiae Snf/Swi complex have been
highly conserved during evolution. Genetic and biochemical evidence suggests that the …

Chromatin is a highly dynamic structure that plays a key role in the orchestration of gene
expression patterns during cellular differentiation and development. The packaging of DNA …

Chromatin assembly in a crude DEAE (CD) fraction from budding yeast is ATP dependent
and generates arrays of physiologically spaced nucleosomes which significantly protect …

ATP-dependent chromatin remodeling factors of SWI/SNF2 family including ISWI, SNF2,
CHD1 and INO80 subfamilies share a conserved but functionally non-interchangeable …

The SWI/SNF chromatin remodeling complex changes the positions where nucleosomes are
bound to DNA, exchanges out histone dimers, and disassembles nucleosomes. All of these …