Angiotensin-converting enzyme 2 (ACE2), a key regulator in vasoregulation and the renin–
angiotensin system, is hypothesized to be downregulated in patients with COVID-19 …

It is hypothesized that several comorbidities increase the severity of COVID‑19 symptoms.
Cardiovascular disease including hypertension was shown to play a critical role in the …

Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is presenting as a systemic disease associated with …

Engulfed by the grave consequences of the coronavirus disease 2019 (COVID-19)
pandemic, a better understanding of the unique pattern of viral invasion and virulence is of …

Clinical evidence reveals that manifestations of endothelial dysfunction are widely observed
in COVID-19 and long-COVID patients. However, whether these detrimental effects are …

One of the hallmarks of the SARS-CoV-2 infection has been the inflammatory process that
played a role in its pathogenesis, resulting in mortality within susceptible individuals. This …

Objective: Coronavirus disease 2019 (COVID-19) is a global pandemic involving> 5 500
000 cases worldwide as of May 26, 2020. The culprit is the severe acute respiratory …

SARS-CoV-2, a novel coronavirus found in Wuhan (China) at the end of 2019, is the
etiological agent of the current pandemic that is a heterogeneous disease, named …

In this short narrative review, we aim at defining the pathophysiological role endothelial
dysfunction in the observed COVID-19–associated rise in risk of cardiovascular disease …

We concisely review clinical, autopsy, experimental and molecular data of 2019 coronavirus
disease (COVID-19). Angiotensin-converting enzyme 2 disruption and thromboinflammatory …