The landscape of realized homologous recombination in pathogenic bacteria

K Yahara, X Didelot, KA Jolley… - Molecular biology …, 2016 - academic.oup.com
Recombination enhances the adaptive potential of organisms by allowing genetic variants to
be tested on multiple genomic backgrounds. Its distribution in the genome can provide …

Evolution of homologous recombination rates across bacteria

EL Torrance, C Burton, A Diop… - Proceedings of the …, 2024 - National Acad Sciences
Bacteria are nonsexual organisms but are capable of exchanging DNA at diverse degrees
through homologous recombination. Intriguingly, the rates of recombination vary immensely …

Efficient inference of recombination hot regions in bacterial genomes

K Yahara, X Didelot, MA Ansari… - Molecular biology …, 2014 - academic.oup.com
In eukaryotes, detailed surveys of recombination rates have shown variation at multiple
genomic scales and the presence of “hotspots” of highly elevated recombination. In bacteria …

Efficient inference of recent and ancestral recombination within bacterial populations

R Mostowy, NJ Croucher, CP Andam… - Molecular biology …, 2017 - academic.oup.com
Prokaryotic evolution is affected by horizontal transfer of genetic material through
recombination. Inference of an evolutionary tree of bacteria thus relies on accurate …

Genome-wide detection and analysis of homologous recombination among sequenced strains of Escherichia coli

B Mau, JD Glasner, AE Darling, NT Perna - Genome Biology, 2006 - Springer
Background Comparisons of complete bacterial genomes reveal evidence of lateral transfer
of DNA across otherwise clonally diverging lineages. Some lateral transfer events result in …

Impact of recombination on bacterial evolution

X Didelot, MCJ Maiden - Trends in microbiology, 2010 - cell.com
Genetic exchange plays a defining role in the evolution of many bacteria. The recent
accumulation of nucleotide sequence data from multiple members of diverse bacterial …

Inference of homologous recombination in bacteria using whole-genome sequences

X Didelot, D Lawson, A Darling, D Falush - Genetics, 2010 - academic.oup.com
Bacteria and archaea reproduce clonally, but sporadically import DNA into their
chromosomes from other organisms. In many of these events, the imported DNA replaces an …

Not so simple after all: bacteria, their population genetics, and recombination

WP Hanage - Cold Spring Harbor perspectives in biology, 2016 - cshperspectives.cshlp.org
The pervasive nature of bacterial recombination has become clear. Despite this, the
population genetics of bacteria persist in being viewed as simple. Here, I argue against that …

Whole genome phylogenies reflect the distributions of recombination rates for many bacterial species

T Sakoparnig, C Field, E van Nimwegen - Elife, 2021 - elifesciences.org
Although recombination is accepted to be common in bacteria, for many species robust
phylogenies with well-resolved branches can be reconstructed from whole genome …

Homologous recombination—experimental systems, analysis, and significance

A Kuzminov - EcoSal Plus, 2011 - Am Soc Microbiol
Homologous recombination is the most complex of all recombination events that shape
genomes and produce material for evolution. Homologous recombination events are …