Background Diabetes mellitus is associated with micro-and macrovascular complications
and increased cardiovascular risk. Elevated levels of serum asymmetric dimethylarginine …

Objectives: Subtle impairment of fetal nutrition appears to predict hypertension and
atherosclerosis in adults. It has been hypothesised that impaired aortic elastogenesis is the …

Background/Aims The aim of this study was to evaluate whether supplementation of high
doses of cholecalciferol for two months in normotensive rats results in increased systolic …

To study the mechanisms of vascular dysfunction in diabetes mellitus, we examined the
responses of the aorta to adrenomedullin (AM) and ANG II in obese Zucker (OZ), lean …

Calcification of the elastic arteries of the young rat by treatment with vitamin D and nicotine
(VDN) has been proposed as an animal model of arterial calcification associated with age …

Background: Vascular complications associated with diabetes are the major cause for the
increased morbidity and mortality in diabetic patients. However, the progression of vascular …

Aims Vascular endothelium is a major organ involved in hyperglycaemia and is affected by
plasma asymmetric dimethylarginine (ADMA). ADMA is an endogenous, competitive …

Objective Endothelial dysfunction plays a pivotal role in the development of diabetic
cardiovascular complications. Accumulation of endogenous nitric oxide synthase (NOS) …

Objective—We hypothesized that ob/ob mice develop expansive vascular remodeling
associated with calcification. Approach and Results—We quantified and investigated …

Polycystic ovary syndrome (PCOS) is associated with elevated cardiovascular risk. Early
vascular dysfunction may lead to the development of cardiovascular disease in PCOS …