Background: Schizophrenia is a complex neuropsychiatric disorder of unclear etiology. The
strongest known genetic risk factor is the 22q11. 2 microdeletion. Research has yet to …

We examined the influence of the genome-wide significant schizophrenia risk variant
rs1625579 near the microRNA (miRNA)-137 (MIR137) gene on well-established sources of …

Since it was first associated with schizophrenia (SCZ) in a 2011 genome‐wide association
study (GWAS), there have been over 100 publications focused on MIR137, the gene …

Genome-wide association studies (GWAS) have identified a region at chromosome 1p21. 3,
containing the microRNA MIR137, to be among the most significant associations for …

Multiple lines of evidence support a role for microRNA 137 (miR-137) in the etiology of
schizophrenia (1–4) and fundamental neuronal processes (5–7). In the largest genome …

Genome-wide association studies (GWAS) have strongly implicated MIR137 (the gene
encoding the microRNA miR-137) in schizophrenia. A parsimonious hypothesis is that a …

The 22q11. 2 deletion is the strongest known genetic risk factor for schizophrenia. Research
has implicated microRNA-mediated dysregulation in 22q11. 2 deletion syndrome (22q11 …

Single nucleotide polymorphisms (SNPs) within the MIR137 gene locus have been shown to
confer risk for schizophrenia through genome-wide association studies (GWAS). The …

Sequence analysis of 13 microRNA (miRNA) genes expressed in the human brain and
located in genomic regions associated with schizophrenia and/or bipolar disorder, in a …

MicroRNAs (miRNAs) are short, non-coding RNAs that regulate the stability and translation
of mRNA targets. Increasing evidence suggests that miRNAs could be involved in the …