Oncogenic activities of human papillomaviruses

ME McLaughlin-Drubin, K Münger - Virus research, 2009 - Elsevier
Infectious etiologies for certain human cancers have long been suggested by
epidemiological studies and studies with experimental animals. Important support for this …

Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis

H Hausen - Journal of the National Cancer Institute, 2000 - academic.oup.com
During the past 20 years, several types of human papillomaviruses (HPVs) have been
identified that cause specific types of cancers. The etiology of cancer of the cervix has been …

Human papillomaviruses and associated malignancies.

RM Alani, K Münger - Journal of clinical oncology, 1998 - ascopubs.org
The human papillomaviruses (HPVS) are small DNA tumor viruses that infect epithelial cells
and induce proliferative lesions. Substantial epidemiologic data along with in vitro and in …

Papillomaviruses in anogenital cancer as a model to understand the role of viruses in human cancers

H zur Hausen - Cancer Research, 1989 - AACR
Infections with specific types of human papillomaviruses (HPV) have emerged as necessary
but not sufficient factors for the development, at least, of the majority of cervical, vulvar …

Human papillomaviruses and carcinomas

DA Galloway, JK McDougall - Advances in virus research, 1989 - Elsevier
Publisher Summary This chapter discusses evidence for the involvement of human
papillomaviruses (HPVs) in squamous-cell carcinomas. Progress in developing an …

Papillomavirus infections—a major cause of human cancers

H Zur Hausen - Biochimica et biophysica acta (BBA)-reviews on cancer, 1996 - Elsevier
The papillomavirus family represents a remarkably heterogeneous group of viruses. At
present, 77 distinct genotypes have been identified in humans and partial sequences have …

[HTML][HTML] Cellular transformation by human papillomaviruses: lessons learned by comparing high-and low-risk viruses

AJ Klingelhutz, A Roman - Virology, 2012 - Elsevier
The oncogenic potential of papillomaviruses (PVs) has been appreciated since the 1930s
yet the mechanisms of virally-mediated cellular transformation are still being revealed …

Papillomaviruses in human cancers

H Zur Hausen - Proceedings of the Association of American …, 1999 - Wiley Online Library
Papillomaviruses have proved to be the most complex group of human pathogenic viruses.
Eighty‐five genotypes have been fully characterized; approximately 120 additional isolates …

In vitro biological activities of the E6 and E7 genes vary among human papillomaviruses of different oncogenic potential

MS Barbosa, WC Vass, DR Lowy, JT Schiller - Journal of virology, 1991 - Am Soc Microbiol
Human papillomavirus type 16 (HPV-16) and HPV-18 are often detected in cervical
carcinomas, while HPV-6, although frequently present in benign genital lesions, is only …

Basic mechanisms of high‐risk human papillomavirus‐induced carcinogenesis: roles of E6 and E7 proteins

M Narisawa‐Saito, T Kiyono - Cancer science, 2007 - Wiley Online Library
Human papillomaviruses (HPV) are believed to be the primary causal agents for
development of pre‐neoplastic and malignant lesions of the uterine cervix, and high‐risk …