The emergence of antimicrobial resistance (AMR) is rapidly increasing and it is one of the
significant twenty-first century's healthcare challenges. Unfortunately, the development of …

Antibodies are potent components of the immune repertoire and have been successfully
exploited to treat bacterial infections. Recently an antibody–antibiotic conjugate (AAC) that …

Antimicrobial peptides (AMPs) are ubiquitous host defense peptides characterized by their
antibiotic activity and lower propensity for developing resistance compared to classic …

Pseudomonas aeruginosa causes life-threatening infections that are associated with
antibiotic failure. Previously, we identified the antibiotic G2637, an analog of arylomycin …

Introduction: Drug conjugates are trend topics in Chemical Biology. These entities are an
emerging class of highly potent biopharmaceutical drugs, best known in the field of …

Covering: up to the end of 2016 Novel antimicrobial drugs are continuously needed to
counteract bacterial resistance development. An innovative molecular design strategy for …

The current global crisis of antibiotic drug resistance is driving the search for novel treatment
approaches. Antimicrobial peptides (AMPs) are small molecular weight proteins with varying …

The growing prevalence of antimicrobial resistance (AMR) has brought with it a continual
increase in the numbers of deaths from multidrug-resistant (MDR) infections. Since the …

The tale of abate in antibiotics continued defense mechanisms that chaperone the rise of
drug-defying superbugs—on the other hand, the astray in antibacterial drug discovery and …

Antibiotics have been widely used in the medical field as a treatment for infectious diseases,
but they are not effective against all Gram-negative bacteria because of their low …