The substantial increase in life expectancy of men has focused growing attention on quality-
of-life issues associated with reproductive aging. Serum total and free testosterone levels in …

Total and free testosterone levels decline in men with advancing age due to defects at all
levels of the hypothalamic-pituitary-testicular axis. Age-related decline in total and free …

In male mammals, changes at all levels of the hypothalamic-pituitary-testicular axis,
including alterations in the GnRH pulse generator, gonadotropin secretion, and testicular …

Western populations represent an ageing society with continuing gains being made in life
expectancy; a male born in Australia has a healthy life expectancy of 70 years with slightly …

Background The prevalence of low testosterone levels in men increases with age, as does
the prevalence of decreased mobility, sexual function, self-perceived vitality, cognitive …

Serum testosterone levels peak in early adulthood in men and fall progressively with age.
Since sex hormone binding globulin increases with age, the unbound forms of testosterone …

A 2003 report by the Institute of Medicine (IOM) surveyed the literature on the benefits and
risks of testosterone replacement therapy in older men and identified knowledge gaps and …

Increased longevity and population aging will increase the number of men with relative
testosterone deficiency, as systemic levels of testosterone decrease by about 1% each year …

Popular culture often equates testosterone with virility, strength, and the macho male
physique. Viewed by some as an" antiaging tonic," testosterone's reputation and increased …

The benefits conferred by testosterone replacement therapy are substantial, both in the short
term for the eradication of symptoms of androgen deficiency, and in the long term for the …