Innate immune response to SARS-CoV-2 infection: From cells to soluble mediators

D Ricci, MP Etna, F Rizzo, S Sandini, M Severa… - International journal of …, 2021 - mdpi.com
The vulnerability of humankind to SARS-CoV-2 in the absence of a pre-existing immunity,
the unpredictability of the infection outcome, and the high transmissibility, broad tissue …

COVID-19: immunology, immunopathogenesis and potential therapies

A Bhardwaj, L Sapra, C Saini, Z Azam… - International reviews …, 2022 - Taylor & Francis
Abstract The Coronavirus Disease-2019 (COVID-19) imposed public health emergency and
affected millions of people around the globe. As of January 2021, 100 million confirmed …

The deciphering of the immune cells and marker signature in COVID‐19 pathogenesis: An update

SA Jasim, RS Mahdi, DO Bokov… - Journal of Medical …, 2022 - Wiley Online Library
The precise interaction between the immune system and severe acute respiratory syndrome
coronavirus 2 (SARS‑CoV‑2) is critical in deciphering the pathogenesis of coronavirus …

A review on the immune responses against novel emerging coronavirus (SARS-CoV-2)

R Lotfi, RN Kalmarzi, SA Roghani - Immunologic research, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by a
newly identified coronavirus called the severe acute respiratory syndrome-coronavirus 2 …

Mechanistic insight into the protective and pathogenic immune-responses against SARS-CoV-2

PK Purbey, K Roy, S Gupta, MK Paul - Molecular Immunology, 2023 - Elsevier
COVID-19 is a severe respiratory illness that has emerged as a devasting health problem
worldwide. The disease outcome is heterogeneous, which is most likely dependent on the …

Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2

M Catanzaro, F Fagiani, M Racchi, E Corsini… - Signal transduction and …, 2020 - nature.com
To date, no vaccines or effective drugs have been approved to prevent or treat COVID-19
and the current standard care relies on supportive treatments. Therefore, based on the fast …

[HTML][HTML] Immunological aspects of COVID-19: What do we know?

TV Velikova, SV Kotsev, DS Georgiev… - World Journal of …, 2020 - ncbi.nlm.nih.gov
The newly emerged coronavirus (severe acute respiratory syndrome coronavirus 2 SARS-
CoV-2) and the disease that it causes coronavirus disease 2019 (COVID-19) have changed …

Innate immune response in SARS-CoV-2 infection

G Schiuma, S Beltrami, D Bortolotti, S Rizzo, R Rizzo - Microorganisms, 2022 - mdpi.com
An efficient host immune response is crucial in controlling viral infections. Despite most
studies focused on the implication of T and B cell response in COVID-19 (Corona Virus …

Immunopathology and Immunopathogenesis of COVID-19, what we know and what we should learn

M Shahgolzari, A Yavari, Y Arjeini, SM Miri, A Darabi… - Gene reports, 2021 - Elsevier
Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) directly interacts
with host's epithelial and immune cells, leading to inflammatory response induction, which is …

[PDF][PDF] COVID-19 and the human innate immune system

JL Schultze, AC Aschenbrenner - Cell, 2021 - cell.com
The introduction of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into the
human population represents a tremendous medical and economic crisis. Innate immunity …