Osteosarcoma (OS) is a primary malignant bone tumor in early adolescence with high
metastasis and death rates. Although the combination of polychemotherapy and surgical …

Osteosarcoma (OS) is known as a malignant bone tumor affecting mainly children and
younger adults. Despite all the improvements in the treatment of OS, the overall survival …

Osteosarcoma (OS) prevailing in children and adolescents mainly occurs at the metaphysis
of long bones. As it is associated with a high invasive and metastatic ability, resistance to …

Osteosarcoma represents the most prevailing primary bone tumor and the third most
common cancer in children and adolescents worldwide. Among noncoding RNAs, circular …

Osteosarcoma is the most common primary bone malignancy and is a neoplasm thought to
be derived from the bone‐forming mesenchymal stem cells. Aberrant activation of …

Circular RNAs (circRNAs) is a novel type of non-coding RNAs generated from back splicing,
which has been verified to mediate multiple tumorigenesis. However, the role of circRNA in …

Circular RNAs (circRNAs) are single-stranded RNAs generated from exons back-splicing
from a single pre-mRNA, forming covalently closed loop structures which lack 5′-3 …

Osteosarcoma is the most common malignant bone tumor in children and adolescents.
Multiagent chemotherapy, together with surgical removal of all detectable lesions, has …

Osteosarcoma is a malignant tumor that occurs most commonly in the metaphysis of the long
bones in the limbs in children and adolescents. Even with surgery and neoadjuvant …

Osteosarcoma is the most common primary malignant bone tumor in young adult, which is
prone to early metastasis and poor prognosis. The current treatment methods need to be …