Optimal therapy for severe pneumococcal community-acquired pneumonia

M Luján, M Gallego, J Rello - Intensive care medicine, 2006 - Springer
Streptococcus pneumoniae is responsible for two-thirds of ICU admissions due to
community-acquired pneumonia (CAP) and is the leading cause of CAP-related death. Early …

The intensive care management, mortality and prognostic indicators in severe community-acquired pneumococcal pneumonia

PD Potgieter, JMJ Hammond - Intensive care medicine, 1996 - Springer
Objective To determine mortality and factors that might predict outcome in severe community-
acquired pneumococcal pneumonia treated by a standard protocol. Design Prospective …

Severity scoring in community-acquired pneumonia caused by Streptococcus pneumoniae: a 5-year experience

OC Ioachimescu, AG Ioachimescu, PB Iannini - International journal of …, 2004 - Elsevier
Multiple severity scoring systems have been devised and evaluated in community-acquired
pneumonia (CAP), but a simplified set of prognostic indicators has not yet been developed …

[HTML][HTML] Severe pneumococcal pneumonia: impact of new quinolones on prognosis

D Olive, H Georges, P Devos, N Boussekey… - BMC infectious …, 2011 - Springer
Background Most guidelines have been proposing, for more than 15 years, a β-lactam
combined with either a quinolone or a macrolide as empirical, first-line therapy of severe …

Severe pneumococcal pneumonia: new strategies for management

CCC Chiou, LY Victor - Current opinion in critical care, 2006 - journals.lww.com
Hospitalized patients with community-acquired pneumonia should have blood cultures
obtained to confirm the possibility of bacteremic pneumococcal pneumonia. Based on …

Optimal antibiotic treatment in severe pneumococcal pneumonia—time for real answers

GW Waterer - European Journal of Clinical Microbiology and …, 2005 - Springer
The large number of guidelines that have been published for the management of community-
acquired pneumonia (CAP) reflects that (i) it is a very common disease,(ii) it is relatively …

What is new in antibiotic therapy in community-acquired pneumonia? An evidence-based approach focusing on combined therapy

S Gattarello - Current infectious disease reports, 2015 - Springer
Despite all published literature, controversies remain about the optimal antibiotic treatment
in community-acquired pneumonia. The most debated issue is whether it is necessary to …

Changing needs of community-acquired pneumonia

JA Ramirez, AR Anzueto - Journal of antimicrobial …, 2011 - academic.oup.com
Community-acquired pneumonia (CAP) is a serious condition associated with significant
morbidity and potential long-term mortality. Although the majority of patients with CAP are …

The role of new therapies for severe community-acquired pneumonia

MI Restrepo, A Anzueto - Current Opinion in Infectious Diseases, 2006 - journals.lww.com
The cost, morbidity and mortality of CAP patients requiring ICU admission remain
unacceptably high. These are heterogeneous groups of patients, so it is important to use risk …

Community-acquired pneumonia: the US perspective

MS Niederman - Seminars in respiratory and critical care …, 2009 - thieme-connect.com
Community-acquired pneumonia (CAP) is a common and serious problem in the United
States, and the sixth leading cause of death in those over age 65. Not only has short-term …