Novel genetic predictors of venous thromboembolism risk in African Americans

W Hernandez, ER Gamazon… - Blood, The Journal …, 2016 - ashpublications.org
Venous thromboembolism (VTE) is the third most common life-threatening cardiovascular
condition in the United States, with African Americans (AAs) having a 30% to 60% higher …

Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism

S Lindström, LU Wang, EN Smith… - Blood, The Journal …, 2019 - ashpublications.org
Venous thromboembolism (VTE) is a significant contributor to morbidity and mortality. To
advance our understanding of the biology contributing to VTE, we conducted a genome …

Cross-ancestry investigation of venous thromboembolism genomic predictors

F Thibord, D Klarin, JA Brody, MH Chen, MG Levin… - Circulation, 2022 - Am Heart Assoc
Background: Venous thromboembolism (VTE) is a life-threatening vascular event with
environmental and genetic determinants. Recent VTE genome-wide association studies …

Identification of unique venous thromboembolism-susceptibility variants in African-Americans

JA Heit, SM Armasu, BM McCauley… - Thrombosis and …, 2017 - thieme-connect.com
To identify novel single nucleotide polymorphisms (SNPs) associated with venous
thromboembolism (VTE) in African-Americans (AAs), we performed a genome-wide …

[HTML][HTML] A genome‐wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24. 2 and 9q

JA Heit, SM Armasu, YW Asmann… - Journal of thrombosis …, 2012 - Elsevier
Objectives: To identify venous thromboembolism (VTE) disease‐susceptibility genes.
Patients and methods: We performed in silico genome wide association scan (GWAS) …

Is there still room for additional common susceptibility alleles for venous thromboembolism?

DA Trégouët, A Delluc, A Roche… - … of Thrombosis and …, 2016 - Wiley Online Library
Essentials Genetic architecture of venous thromboembolism (VTE) remains to be fully
disentangled. 11 newly discovered candidate polymorphisms were genotyped in 3019 VTE …

[PDF][PDF] Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism

M Germain, DI Chasman, H De Haan, W Tang… - The American Journal of …, 2015 - cell.com
Venous thromboembolism (VTE), the third leading cause of cardiovascular mortality, is a
complex thrombotic disorder with environmental and genetic determinants. Although several …

Single-and multimarker genome-wide scans evidence novel genetic risk modifiers for venous thromboembolism

M Herrera-Rivero, M Stoll… - Thrombosis and …, 2021 - thieme-connect.com
Previous genome-wide association studies (GWASs) have established several susceptibility
genes for venous thromboembolism (VTE) and suggested many others. However, a large …

A genome‐wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium

W Tang, M Teichert, DI Chasman, JA Heit… - Genetic …, 2013 - Wiley Online Library
Venous thromboembolism (VTE) is a common, heritable disease resulting in high rates of
hospitalization and mortality. Yet few associations between VTE and genetic variants, all in …

A large‐scale exome array analysis of venous thromboembolism

S Lindström, JA Brody, C Turman… - Genetic …, 2019 - Wiley Online Library
Abstract Although recent Genome‐Wide Association Studies have identified novel
associations for common variants, there has been no comprehensive exome‐wide search …