Acute respiratory distress syndrome (ARDS) and robust cytokine storm are the hallmark of
severe COVID-19 cases. Using single-cell RNA sequencing of bronchoalveolar lavage fluid …

Acute respiratory distress syndrome (ARDS) and robust cytokine storm are the hallmark of
severe COVID-19 cases. Using single-cell RNA sequencing of bronchoalveolar lavage fluid …

The exaggerated immune response induced in the lower respiratory tract against
coronaviruses (CoVs), including CoViD-19 (2019-nCoV), appears to contribute to the …

Clinical evidence indicates that the fatal outcome observed with severe acute respiratory
syndrome-coronavirus-2 infection often results from alveolar injury that impedes airway …

The pathogenesis of pandemic coronavirus disease-2019 (COVID-19) caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) likely depends heavily on …

The dysregulated release of cytokines has been identified as one of the key factors behind
poorer outcomes in COVID-19. This “cytokine storm” produces an excessive inflammatory …

Immune response dynamics in coronavirus disease 2019 (COVID-19) and their severe
manifestations have largely been studied in circulation. Here, we examined the relationship …

Pathogenic human coronavirus infections, such as severe acute respiratory syndrome CoV
(SARS-CoV) and Middle East respiratory syndrome CoV (MERS-CoV), cause high morbidity …

Recent studies have demonstrated immunologic dysfunction in severely ill coronavirus
disease 2019 (COVID-19) patients. We use single-cell RNA sequencing (scRNA-seq) to …

Respiratory tract infection with SARS-CoV-2 results in varying immunopathology underlying
COVID-19. We examine cellular, humoral and cytokine responses covering 382 immune …