Early differences in cytokine production by severity of coronavirus disease 2019

LH Tjan, K Furukawa, T Nagano, T Kiriu… - The Journal of …, 2021 - academic.oup.com
Most patients with coronavirus disease 2019 (COVID-19) experience asymptomatic disease
or mild symptoms, but some have critical symptoms requiring intensive care. It is important to …

Respiratory and systemic monocytes, dendritic cells, and myeloid‐derived suppressor cells in COVID‐19: Implications for disease severity

S Falck‐Jones, B Österberg… - Journal of Internal …, 2023 - Wiley Online Library
Since the beginning of the SARS‐CoV‐2 pandemic in 2020, researchers worldwide have
made efforts to understand the mechanisms behind the varying range of COVID‐19 disease …

Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19

AHE Roukens, CR Pothast, M König, W Huisman… - Nature …, 2022 - nature.com
Systemic immune cell dynamics during coronavirus disease 2019 (COVID-19) are
extensively documented, but these are less well studied in the (upper) respiratory tract …

Compartmental immunophenotyping in COVID-19 ARDS: A case series

A Ronit, RMG Berg, JT Bay, AK Haugaard… - Journal of Allergy and …, 2021 - Elsevier
Background Severe immunopathology may drive the deleterious manifestations that are
observed in the advanced stages of coronavirus disease 2019 (COVID-19) but are poorly …

A shift in lung macrophage composition is associated with COVID-19 severity and recovery

ST Chen, MD Park, DM Del Valle, M Buckup… - Science translational …, 2022 - science.org
Although it has been more than 2 years since the start of the coronavirus disease 2019
(COVID-19) pandemic, COVID-19 continues to be a worldwide health crisis. Despite the …

COVID-19: more than a cytokine storm

G Riva, V Nasillo, E Tagliafico, T Trenti, P Comoli… - Critical care, 2020 - Springer
Background In these first months of coronavirus disease-19 (COVID-19) pandemic, a
mainstream pathogenetic hypothesis, likely stemming from early clinico-therapeutic …

Immune dysfunction leads to mortality and organ injury in patients with COVID-19 in China: insights from ERS-COVID-19 study

D Li, Y Chen, H Liu, Y Jia, F Li, W Wang, J Wu… - … and Targeted Therapy, 2020 - nature.com
A series of novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) since the end of 2019 is ongoing and triggering a …

Deciphering the COVID‐19 cytokine storm: systematic review and meta‐analysis

R Mulchandani, T Lyngdoh… - European journal of …, 2021 - Wiley Online Library
Introduction The coronavirus pandemic has affected more than 20 million people so far.
Elevated cytokines and suppressed immune responses have been hypothesized to set off a …

The role of cytokines and chemokines in severe acute respiratory syndrome coronavirus 2 infections

RJ Hsu, WC Yu, GR Peng, CH Ye, SY Hu… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …

Deciphering the state of immune silence in fatal COVID-19 patients

P Bost, F De Sanctis, S Canè, S Ugel… - Nature …, 2021 - nature.com
Since the beginning of the SARS-CoV-2 pandemic, COVID-19 appeared as a unique
disease with unconventional tissue and systemic immune features. Here we show a COVID …