Natural killer cell immunotypes related to COVID-19 disease severity

C Maucourant, I Filipovic, A Ponzetta, S Aleman… - Science …, 2020 - science.org
Understanding innate immune responses in coronavirus disease 2019 (COVID-19) is
important to decipher mechanisms of host responses and interpret disease pathogenesis …

Defining the role of natural killer cells in COVID-19

MJ Lee, CA Blish - Nature Immunology, 2023 - nature.com
Natural killer (NK) cells are critical effectors of antiviral immunity. Researchers have
therefore sought to characterize the NK cell response to coronavirus disease 2019 (COVID …

[HTML][HTML] Flattening the COVID-19 curve with natural killer cell based immunotherapies

M Market, L Angka, AB Martel, D Bastin… - Frontiers in …, 2020 - frontiersin.org
Natural Killer (NK) cells are innate immune responders critical for viral clearance and
immunomodulation. Despite their vital role in viral infection, the contribution of NK cells in …

[HTML][HTML] Natural killer cells in antiviral immunity

NK Björkström, B Strunz, HG Ljunggren - Nature Reviews Immunology, 2022 - nature.com
Natural killer (NK) cells play an important role in innate immune responses to viral infections.
Here, we review recent insights into the role of NK cells in viral infections, with particular …

[PDF][PDF] Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19

B Krämer, R Knoll, L Bonaguro, M ToVinh, J Raabe… - Immunity, 2021 - cell.com
Longitudinal analyses of the innate immune system, including the earliest time points, are
essential to understand the immunopathogenesis and clinical course of coronavirus disease …

[HTML][HTML] Natural killer cells in SARS-CoV-2 infection: pathophysiology and therapeutic implications

C Di Vito, F Calcaterra, N Coianiz, S Terzoli… - Frontiers in …, 2022 - frontiersin.org
Natural Killer (NK) cells are lymphocytes of the innate immunity that play a crucial role in the
control of viral infections in the absence of a prior antigen sensitization. Indeed, they display …

Abnormality in the NK-cell population is prolonged in severe COVID-19 patients

G Leem, S Cheon, H Lee, SJ Choi, S Jeong… - Journal of Allergy and …, 2021 - Elsevier
Background Our understanding of adaptive immune responses in patients with coronavirus
disease 2019 (COVID-19) is rapidly evolving, but information on the innate immune …

[HTML][HTML] Severe COVID-19 patients display hyper-activated NK cells and NK cell-platelet aggregates

B Malengier-Devlies, J Filtjens, K Ahmadzadeh… - Frontiers in …, 2022 - frontiersin.org
COVID-19 is characterised by a broad spectrum of clinical and pathological features. Natural
killer (NK) cells play an important role in innate immune responses to viral infections. Here …

NK cells: A double edge sword against SARS-CoV-2

E Masselli, M Vaccarezza, C Carubbi, G Pozzi… - Advances in biological …, 2020 - Elsevier
Natural killer (NK) cells are pivotal effectors of the innate immunity protecting an individual
from microbes. They are the first line of defense against invading viruses, given their …

[HTML][HTML] Natural killer cell dysfunction and its role in COVID-19

C van Eeden, L Khan, MS Osman… - International journal of …, 2020 - mdpi.com
When facing an acute viral infection, our immune systems need to function with finite
precision to enable the elimination of the pathogen, whilst protecting our bodies from …