[HTML][HTML] Natural killer cells and unconventional T cells in COVID-19

NK Björkström, A Ponzetta - Current Opinion in Virology, 2021 - Elsevier
Highlights•NK cells and unconventional T cells are robustly activated in SARS-CoV-2
infection.•Both populations of cells also home to lung tissue during acute infection.•Severe …

Identification of druggable inhibitory immune checkpoints on Natural Killer cells in COVID-19

O Demaria, J Carvelli, L Batista, ML Thibult… - Cellular & molecular …, 2020 - nature.com
Infection with SARS-COV-2 is the cause of COVID-19 and has generated an unprecedented
health crisis worldwide. While most of the patients experience mild symptoms, around 20 …

Can natural killer cells be a principal player in anti-SARS-CoV-2 immunity?

F Ahmed, DH Jo, SH Lee - Frontiers in immunology, 2020 - frontiersin.org
The spread of the coronavirus disease 2019 (COVID-19) pandemic has led to disastrous
consequences, impacting social, economic, and medical systems, spanning both developed …

Impaired natural killer cell counts and cytolytic activity in patients with severe COVID-19

M Osman, RM Faridi, W Sligl, MT Shabani-Rad… - Blood …, 2020 - ashpublications.org
The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–
driven coronavirus disease 2019 (COVID-19) has caused unprecedented human death and …

Natural killer cells play an important role in virus infection control: Antiviral mechanism, subset expansion and clinical application

W Zuo, X Zhao - Clinical Immunology, 2021 - Elsevier
With the global spread of coronavirus disease 2019 (COVID-19), the important role of
natural killer (NK) cells in the control of various viral infections attracted more interest, via …

Natural killer cells in COVID-19: from infection, to vaccination and therapy

A Zafarani, MH Razizadeh, S Pashangzadeh… - Future …, 2023 - Taylor & Francis
Natural killer (NK) cells are among the most important innate immunity members, which are
the first cells that fight against infected cells. The function of these cells is impaired in …

Extensive activation, tissue trafficking, turnover and functional impairment of NK cells in COVID-19 patients at disease onset associates with subsequent disease …

F Bozzano, C Dentone, C Perrone, A Di Biagio… - PLoS …, 2021 - journals.plos.org
The SARS-CoV-2 infection causes severe respiratory involvement (COVID-19) in 5–20% of
patients through initial immune derangement, followed by intense cytokine production and …

Natural killer cell‐mediated ADCC in SARS‐CoV‐2‐infected individuals and vaccine recipients

K Hagemann, K Riecken, JM Jung… - European journal of …, 2022 - Wiley Online Library
Abstract COVID‐19, caused by SARS‐CoV‐2, has emerged as a global pandemic. While
immune responses of the adaptive immune system have been in the focus of research, the …

Natural killer-cell immunoglobulin-like receptors trigger differences in immune response to SARS-CoV-2 infection

R Littera, L Chessa, S Deidda, G Angioni… - PloS One, 2021 - journals.plos.org
Background The diversity in the clinical course of COVID-19 has been related to differences
in innate and adaptative immune response mechanisms. Natural killer (NK) lymphocytes are …

Major reduction of NKT cells in patients with severe COVID-19 pneumonia

MA Zingaropoli, V Perri, P Pasculli, FC Dezza… - Clinical …, 2021 - Elsevier
Background NK cells seem to be mainly involved in COVID-19 pneumonia. Little is known
about NKT cells which represent a bridge between innate and adaptive immunity. Methods …