[HTML][HTML] Single-cell sequencing of peripheral mononuclear cells reveals distinct immune response landscapes of COVID-19 and influenza patients
Summary The coronavirus disease 2019 (COVID-19) pandemic poses a current world-wide
public health threat. However, little is known about its hallmarks compared to other infectious …
public health threat. However, little is known about its hallmarks compared to other infectious …
Immunologic perturbations in severe COVID-19/SARS-CoV-2 infection
L Kuri-Cervantes, MB Pampena, W Meng… - BioRxiv, 2020 - biorxiv.org
Although critical illness has been associated with SARS-CoV-2-induced hyperinflammation,
the immune correlates of severe COVID-19 remain unclear. Here, we comprehensively …
the immune correlates of severe COVID-19 remain unclear. Here, we comprehensively …
Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19
AHE Roukens, CR Pothast, M König, W Huisman… - Nature …, 2022 - nature.com
Systemic immune cell dynamics during coronavirus disease 2019 (COVID-19) are
extensively documented, but these are less well studied in the (upper) respiratory tract …
extensively documented, but these are less well studied in the (upper) respiratory tract …
MHC Variants Associated With Symptomatic Versus Asymptomatic SARS-CoV-2 Infection in Highly Exposed Individuals
Despite the high number of individuals infected by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) who develop coronavirus disease 2019 (COVID-19) symptoms …
coronavirus 2 (SARS-CoV-2) who develop coronavirus disease 2019 (COVID-19) symptoms …
Severe COVID-19 is marked by a dysregulated myeloid cell compartment
J Schulte-Schrepping, N Reusch, D Paclik, K Baßler… - Cell, 2020 - cell.com
Summary Coronavirus disease 2019 (COVID-19) is a mild to moderate respiratory tract
infection, however, a subset of patients progress to severe disease and respiratory failure …
infection, however, a subset of patients progress to severe disease and respiratory failure …
Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells
M Witkowski, C Tizian, M Ferreira-Gomes, D Niemeyer… - Nature, 2021 - nature.com
SARS-CoV-2 is a single-stranded RNA virus that causes COVID-19. Given its acute and
often self-limiting course, it is likely that components of the innate immune system play a …
often self-limiting course, it is likely that components of the innate immune system play a …
[HTML][HTML] COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas
A dysfunctional immune response in coronavirus disease 2019 (COVID-19) patients is a
recurrent theme impacting symptoms and mortality, yet a detailed understanding of pertinent …
recurrent theme impacting symptoms and mortality, yet a detailed understanding of pertinent …
Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans
Coronavirus disease 2019 (COVID-19) represents a global crisis, yet major knowledge gaps
remain about human immunity to severe acute respiratory syndrome coronavirus 2 (SARS …
remain about human immunity to severe acute respiratory syndrome coronavirus 2 (SARS …
Deciphering the state of immune silence in fatal COVID-19 patients
Since the beginning of the SARS-CoV-2 pandemic, COVID-19 appeared as a unique
disease with unconventional tissue and systemic immune features. Here we show a COVID …
disease with unconventional tissue and systemic immune features. Here we show a COVID …
Distinct inflammatory profiles distinguish COVID-19 from influenza with limited contributions from cytokine storm
PA Mudd, JC Crawford, JS Turner, A Souquette… - Science …, 2020 - science.org
We pursued a study of immune responses in coronavirus disease 2019 (COVID-19) and
influenza patients. Compared to patients with influenza, patients with COVID-19 exhibited …
influenza patients. Compared to patients with influenza, patients with COVID-19 exhibited …