Immunobiology of COVID-19: Mechanistic and therapeutic insights from animal models

HY Zheng, TZ Song, YT Zheng - Zoological research, 2024 - pubmed.ncbi.nlm.nih.gov
The distribution of the immune system throughout the body complicates in vitro assessments
of coronavirus disease 2019 (COVID-19) immunobiology, often resulting in a lack of …

[HTML][HTML] Experimental animal models of coronavirus infections: strengths and limitations

MAB Casel, RG Rollon, YK Choi - Immune Network, 2021 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). Since the emergence of SARS-CoV-2 in the human …

Animal models of COVID-19 II. Comparative immunology

RT Veenhuis, CJ Zeiss - ILAR journal, 2021 - academic.oup.com
Developing strong animal models is essential for furthering our understanding of how the
immune system functions in response to Severe Acute Respiratory Syndrome Coronavirus 2 …

[PDF][PDF] ACTIVating resources for the COVID-19 pandemic: in vivo models for vaccines and therapeutics

JA Hewitt, C Lutz, WC Florence, MLM Pitt, S Rao… - Cell Host & Microbe, 2020 - cell.com
The Preclinical Working Group of Accelerating COVID-19 Therapeutic Interventions and
Vaccines (ACTIV), a public-private partnership spearheaded by the National Institutes of …

SARS-CoV-2 immunity in animal models

Z Chen, Y Yuan, Q Hu, A Zhu, F Chen, S Li… - Cellular & Molecular …, 2024 - nature.com
The COVID-19 pandemic, which was caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has become a worldwide health crisis due to its …

Immunology Lessons from the SARS-CoV-2 Pandemic

WM Yokoyama, KA Hogquist… - Annual Review of …, 2021 - annualreviews.org
We are one year into the pandemic with severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19). Much has …

Thinking Outside the Box: Utilizing Nontraditional Animal Models for COVID-19 Research

S Gunasekara, M Tamil Selvan, CA Miller… - International Journal of …, 2022 - mdpi.com
The ongoing COVID-19 pandemic continues to affect the lives, wellbeing, and stability of
communities worldwide. The race to save human lives is critical, and the development of …

[HTML][HTML] Potential mouse models of coronavirus-related immune injury

FY Nan, CJ Wu, JH Su, LQ Ma - Frontiers in immunology, 2022 - frontiersin.org
Basic research for prevention and treatment of coronavirus disease 2019 (COVID-19),
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues …

Mouse models in COVID-19 research: analyzing the adaptive immune response

S Clever, A Volz - Medical microbiology and immunology, 2023 - Springer
The emergence of SARS-CoV-2, the severe acute respiratory syndrome coronavirus type 2
causing the COVID-19 pandemic, resulted in a major necessity for scientific …

Animal models of SARS-CoV-2 infection and mechanisms of COVID-19

S Cleary, S Pitchford, R Amison, R Carrington… - Authorea …, 2020 - authorea.com
The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 infections
has led to substantial unmet need for treatments, many of which will require testing in …