Characterizing and targeting inflammation in COVID-19 using a rhesus macaque model of SARS-CoV-2 infection

E Viox - 2024 - etd.library.emory.edu
Abstract The Coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in over 6.9 million deaths …

Defining the Syrian hamster as a highly susceptible preclinical model for SARS-CoV-2 infection

K Rosenke, K Meade-White, M Letko… - Emerging microbes & …, 2020 - Taylor & Francis
Following emergence in late 2019, SARS-CoV-2 rapidly became pandemic and is presently
responsible for millions of infections and hundreds of thousands of deaths worldwide. There …

Experimental models of COVID-19

LA Caldera-Crespo, MJ Paidas, S Roy… - Frontiers in cellular …, 2022 - frontiersin.org
COVID-19 is the most consequential pandemic of the 21st century. Since the earliest stage
of the 2019-2020 epidemic, animal models have been useful in understanding the …

Animal models for SARS-CoV-2

CY Lee, AC Lowen - Current opinion in virology, 2021 - Elsevier
Since its first detection in December 2019, severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) has rapidly spread worldwide, resulting in over 79.2 million documented …

[PDF][PDF] Animal Models of COVID-19 for Vaccine and Therapeutic Development

M Hu - 2021 - terra-docs.s3.us-east-2.amazonaws …
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in late
2019 poses an imminent global health crisis. There is an urgent need to develop effective …

Establishment of an African green monkey model for COVID-19 and protection against re-infection

C Woolsey, V Borisevich, AN Prasad, KN Agans… - Nature …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for an
unprecedented global pandemic of COVID-19. Animal models are urgently needed to study …

[HTML][HTML] Immune responses to SARS-CoV-2 infection in Humans and ACE2 humanized mice

A Zhu, Z Chen, Y Wang, Q Zeng, J Sun, Z Zhuang… - Fundamental …, 2021 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) represents a major public health threat …

Comprehensive analysis of disease pathology in immunocompetent and immunocompromised hamster models of SARS-CoV-2 infection

S Ramasamy, A Kolloli, R Kumar, S Husain… - bioRxiv, 2022 - biorxiv.org
The pathogenesis of SARS-CoV-2 in the context of a specific immunological niche is not
fully understood. Here, we used a golden Syrian hamster model to systematically evaluate …

[PDF][PDF] Immunology of COVID-19: current state of the science

M Agrawal, M Aleynick, M Belabed, G Britton, M Brown… - 2020 - psychscenehub.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic, caused by Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has affected millions of people …

In vitro and animal models for SARS-CoV-2 research

K Takayama - Trends in pharmacological sciences, 2020 - cell.com
Basic research on SARS-CoV-2 is essential to understand its detailed pathophysiology and
identify best drug targets. Models that can faithfully reproduce the viral life cycle and …