Animal models for the study of SARS-CoV-2–induced respiratory disease and pathology
JA Dillard, SA Martinez, JJ Dearing… - Comparative …, 2023 - ingentaconnect.com
Emergence of the betacoronavirus SARS-CoV-2 has resulted in a historic pandemic, with
millions of deaths worldwide. An unprecedented effort has been made by the medical …
millions of deaths worldwide. An unprecedented effort has been made by the medical …
Generation of a broadly useful model for COVID-19 pathogenesis, vaccination, and treatment
Summary COVID-19, caused by SARS-CoV-2, is a virulent pneumonia, with> 4,000,000
confirmed cases worldwide and> 290,000 deaths as of May 15, 2020. It is critical that …
confirmed cases worldwide and> 290,000 deaths as of May 15, 2020. It is critical that …
[HTML][HTML] Immune responses to human respiratory coronaviruses infection in mouse models
Z Zhuang, D Liu, J Sun, F Li, J Zhao - Current Opinion in Virology, 2022 - Elsevier
Highlights•Mouse models are useful for understanding immunopathogenesis in HCoV
infections.•Regulated interferon responses is critical for protection from severe …
infections.•Regulated interferon responses is critical for protection from severe …
Disruption of adaptive immunity enhances disease in SARS-CoV-2-infected Syrian hamsters
RL Brocato, LM Principe, RK Kim, X Zeng… - Journal of …, 2020 - Am Soc Microbiol
Animal models recapitulating human COVID-19 disease, especially severe disease, are
urgently needed to understand pathogenesis and to evaluate candidate vaccines and …
urgently needed to understand pathogenesis and to evaluate candidate vaccines and …
Overview of nonhuman primate models of SARS-CoV-2 infection
AM Trichel - Comparative Medicine, 2021 - ingentaconnect.com
COVID-19, the disease caused by the SARS-CoV-2 betacoronavirus, was declared a
pandemic by the World Health Organization on March 11, 2020. Since then, SARS-CoV-2 …
pandemic by the World Health Organization on March 11, 2020. Since then, SARS-CoV-2 …
Pathogenesis guided therapeutic management of COVID-19: an immunological perspective
Lack of standardized therapeutic approaches is arguably the significant contributor to the
high burden of mortality observed in the ongoing pandemic of the Coronavirus disease …
high burden of mortality observed in the ongoing pandemic of the Coronavirus disease …
[图书][B] The Host Response to SARS-CoV-2 and Testing of Therapeutics against COVID-19
R Møller - 2021 - search.proquest.com
The emergence of SARS-CoV-2 and the pandemic of COVID-19 that followed have caused
societal disruption and a significant loss of human lives. The pathology of COVID-19 is …
societal disruption and a significant loss of human lives. The pathology of COVID-19 is …
Animal models of COVID-19: Nonhuman primates
DK Singh, J Cole, RA Escobedo, KJ Alfson… - SARS-CoV-2: Methods …, 2022 - Springer
With the advent of the novel SARS-CoV-2, the entire world has been thrown into chaos with
severe disruptions from a normal life. While the entire world was going chaotic, the …
severe disruptions from a normal life. While the entire world was going chaotic, the …
SARS-CoV-2 infection and disease outcomes in non-human primate models: advances and implications
ABSTRACT SARS-CoV-2 has been the causative pathogen of the pandemic of COVID-19,
resulting in catastrophic health issues globally. It is important to develop human-like animal …
resulting in catastrophic health issues globally. It is important to develop human-like animal …
Alternatives to animal models and their application in the discovery of species susceptibility to SARS-CoV-2 and other respiratory infectious pathogens: A review
S Runft, I Faerber, J Krueger, N Krueger… - Veterinary …, 2022 - journals.sagepub.com
The emergence of the coronavirus disease 2019 (COVID-19) caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) inspired rapid research efforts targeting …
respiratory syndrome coronavirus 2 (SARS-CoV-2) inspired rapid research efforts targeting …