The emerging role of immune checkpoint inhibitors in the treatment of triple-negative breast cancer

S Singh, A Numan, B Maddiboyina, S Arora, Y Riadi… - Drug discovery today, 2021 - Elsevier
Highlights•TNBCs is one of the most heterogenous form of breast cancer appear to have
elevated numbers of immune cells infiltration.•Using immune checkpoint inhibitors (ICIs) …

Role of immunotherapy in triple-negative breast cancer

TE Keenan, SM Tolaney - Journal of the National Comprehensive Cancer …, 2020 - jnccn.org
Immune checkpoint inhibitors (ICIs) have led to durable clinical remissions in many
metastatic cancers. However, the single-agent efficacy of ICIs in breast cancer is low …

Immunotherapy in triple negative breast cancer: beyond checkpoint inhibitors

Y Abdou, A Goudarzi, JX Yu, S Upadhaya… - NPJ Breast …, 2022 - nature.com
The development of immunotherapy agents has revolutionized the field of oncology. The
only FDA-approved immunotherapeutic approach in breast cancer consists of immune …

Immunotherapy for triple-negative breast cancer: combination strategies to improve outcome

L Li, F Zhang, Z Liu, Z Fan - Cancers, 2023 - mdpi.com
Simple Summary For decades, countless efforts have been devoted to developing targeted
drugs to improve the prognosis of triple-negative breast cancer (TNBC). Among the novel …

Immune checkpoint inhibition for triple-negative breast cancer: current landscape and future perspectives

H Yi, Y Li, Y Tan, S Fu, F Tang, X Deng - Frontiers in oncology, 2021 - frontiersin.org
Triple-negative breast cancer (TNBC) is characterized by the lack of clinically significant
levels of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth …

Immune checkpoint inhibitors in triple negative breast cancer treatment: promising future prospects

R Thomas, G Al-Khadairi, J Decock - Frontiers in oncology, 2021 - frontiersin.org
Immunotherapy has emerged as the fifth pillar of cancer treatment alongside surgery,
radiotherapy, chemotherapy, and targeted therapy. Immune checkpoint inhibitors are the …

Immunotherapy treatment for triple negative breast cancer

ER Berger, T Park, A Saridakis, M Golshan… - Pharmaceuticals, 2021 - mdpi.com
Triple-negative breast cancer (TNBC) is considered one of the highest-risk subtypes of
breast cancer and has dismal prognosis. Local recurrence rate after standard therapy in the …

The role of immune checkpoint inhibition in triple negative breast cancer

K Tarekegn, M Keskinkilic, TJ Kristoff… - Expert Review of …, 2023 - Taylor & Francis
Introduction Immunotherapy has revolutionized cancer treatment, including TNBC, which
has limited options of treatment and poor prognosis. ICIs studied in TNBC include …

Checkpoint inhibitors in triple‐negative breast cancer (TNBC): Where to go from here

MJ Kwa, S Adams - Cancer, 2018 - Wiley Online Library
Advances in cancer immunotherapy and a growing body of research have focused on the
role of the antitumor response in breast cancer. Triple‐negative breast cancer (TNBC) is the …

[HTML][HTML] Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of breast cancer

LA Emens, S Adams, A Cimino-Mathews… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Breast cancer has historically been a disease for which immunotherapy was largely
unavailable. Recently, the use of immune checkpoint inhibitors (ICIs) in combination with …