Astrocytes: GABAceptive and GABAergic cells in the brain

J Liu, X Feng, Y Wang, X Xia, JC Zheng - Frontiers in cellular …, 2022 - frontiersin.org
Astrocytes, the most numerous glial cells in the brain, play an important role in preserving
normal neural functions and mediating the pathogenesis of neurological disorders. Recent …

GABAergic interneuron to astrocyte signalling: a neglected form of cell communication in the brain

G Losi, L Mariotti, G Carmignoto - … Transactions of the …, 2014 - royalsocietypublishing.org
GABAergic interneurons represent a minority of all cortical neurons and yet they efficiently
control neural network activities in all brain areas. In parallel, glial cell astrocytes exert a …

GABA release from astrocytes in health and disease

W Kilb, S Kirischuk - International Journal of Molecular Sciences, 2022 - mdpi.com
Astrocytes are the most abundant glial cells in the central nervous system (CNS) mediating a
variety of homeostatic functions, such as spatial K+ buffering or neurotransmitter reuptake. In …

Astrocytes as GABA-ergic and GABA-ceptive cells

BE Yoon, J Woo, C Justin Lee - Neurochemical research, 2012 - Springer
GABA (gamma-aminobutyric acid) is considered to be the major inhibitory neurotransmitter
that is synthesized in and released from GABA-ergic neurons in the brain. However, recent …

Astrocytes regulate inhibitory neurotransmission through GABA uptake, metabolism, and recycling

JV Andersen, A Schousboe… - Essays in …, 2023 - portlandpress.com
Synaptic regulation of the primary inhibitory neurotransmitter γ-aminobutyric acid (GABA) is
essential for brain function. Cerebral GABA homeostasis is tightly regulated through multiple …

Central role of GABA in neuron–glia interactions

M Vélez-Fort, E Audinat, MC Angulo - The Neuroscientist, 2012 - journals.sagepub.com
The major types of glial cells—astrocytes, microglia, and cells of the oligodendroglial
lineage—are known to express functional metabotropic and ionotropic GABA receptors …

GABA as a rising gliotransmitter

BE Yoon, CJ Lee - Frontiers in neural circuits, 2014 - frontiersin.org
Gamma-amino butyric acid (GABA) is the major inhibitory neurotransmitter that is known to
be synthesized and released from GABAergic neurons in the brain. However, recent studies …

Expression and function of GABA receptors in myelinating cells

MP Serrano-Regal, L Bayón-Cordero… - Frontiers in cellular …, 2020 - frontiersin.org
Myelin facilitates the fast transmission of nerve impulses and provides metabolic support to
axons. Differentiation of oligodendrocyte progenitor cells (OPCs) and Schwann cell (SC) …

Olig2-lineage astrocytes: a distinct subtype of astrocytes that differs from GFAP astrocytes

K Tatsumi, A Isonishi, M Yamasaki, Y Kawabe… - Frontiers in …, 2018 - frontiersin.org
Astrocytes are the most abundant glia cell type in the central nervous system (CNS), and are
known to constitute heterogeneous populations that differ in their morphology, gene …

Oligodendroglial GABAergic signaling: more than inhibition!

X Bai, F Kirchhoff, A Scheller - Neuroscience bulletin, 2021 - Springer
GABA is the main inhibitory neurotransmitter in the CNS acting at two distinct types of
receptor: ligand-gated ionotropic GABAA receptors and G protein-coupled metabotropic …