[HTML][HTML] Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology

R Channappanavar, S Perlman - Seminars in immunopathology, 2017 - Springer
Human coronaviruses (hCoVs) can be divided into low pathogenic and highly pathogenic
coronaviruses. The low pathogenic CoVs infect the upper respiratory tract and cause mild …

[HTML][HTML] Human coronaviruses: a review of virus–host interactions

YX Lim, YL Ng, JP Tam, DX Liu - Diseases, 2016 - mdpi.com
Human coronaviruses (HCoVs) are known respiratory pathogens associated with a range of
respiratory outcomes. In the past 14 years, the onset of severe acute respiratory syndrome …

Human coronavirus: host-pathogen interaction

TS Fung, DX Liu - Annual review of microbiology, 2019 - annualreviews.org
Human coronavirus (HCoV) infection causes respiratory diseases with mild to severe
outcomes. In the last 15 years, we have witnessed the emergence of two zoonotic, highly …

Coronavirus infections and immune responses

G Li, Y Fan, Y Lai, T Han, Z Li, P Zhou… - Journal of medical …, 2020 - Wiley Online Library
Coronaviruses (CoVs) are by far the largest group of known positive‐sense RNA viruses
having an extensive range of natural hosts. In the past few decades, newly evolved …

[HTML][HTML] Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses—are we our own worst enemy?

LYR Wong, S Perlman - Nature Reviews Immunology, 2022 - nature.com
Human coronaviruses cause a wide spectrum of disease, ranging from mild common colds
to acute respiratory distress syndrome and death. Three highly pathogenic human …

Human cell tropism and innate immune system interactions of human respiratory coronavirus EMC compared to those of severe acute respiratory syndrome …

F Zielecki, M Weber, M Eickmann… - Journal of …, 2013 - Am Soc Microbiol
Infections with human coronavirus EMC (HCoV-EMC) are associated with severe
pneumonia. We demonstrate that HCoV-EMC resembles severe acute respiratory syndrome …

Molecular pathology of emerging coronavirus infections

LE Gralinski, RS Baric - The Journal of pathology, 2015 - Wiley Online Library
Respiratory viruses can cause a wide spectrum of pulmonary diseases, ranging from mild,
upper respiratory tract infections to severe and life‐threatening lower respiratory tract …

Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus

L Josset, VD Menachery, LE Gralinski, S Agnihothram… - MBio, 2013 - Am Soc Microbiol
ABSTRACT A novel human coronavirus (HCoV-EMC) was recently identified in the Middle
East as the causative agent of a severe acute respiratory syndrome (SARS) resembling the …

[HTML][HTML] Coronavirus infections: Epidemiological, clinical and immunological features and hypotheses

D Raoult, A Zumla, F Locatelli, G Ippolito, G Kroemer - Cell stress, 2020 - ncbi.nlm.nih.gov
Coronaviruses (CoVs) are a large family of enveloped, positive-strand RNA viruses. Four
human CoVs (HCoVs), the non-severe acute respiratory syndrome (SARS)-like HCoVs …

A tug-of-war between severe acute respiratory syndrome coronavirus 2 and host antiviral defence: lessons from other pathogenic viruses

SY Fung, KS Yuen, ZW Ye, CP Chan… - Emerging microbes & …, 2020 - Taylor & Francis
ABSTRACT World Health Organization has declared the ongoing outbreak of coronavirus
disease 2019 (COVID-19) a Public Health Emergency of International Concern. The virus …