Plasma miRNA profile at COVID-19 onset predicts severity status and mortality

A Fernández-Pato, A Virseda-Berdices… - Emerging microbes & …, 2022 - Taylor & Francis
Background MicroRNAs (miRNAs) have a crucial role in regulating immune response
against infectious diseases, showing changes early in disease onset and before the …

[HTML][HTML] Circulating microRNA signatures associated with disease severity and outcome in COVID-19 patients

A Giannella, S Riccetti, A Sinigaglia, C Piubelli… - Frontiers in …, 2022 - frontiersin.org
Background SARS-CoV-2 induces a spectrum of clinical conditions ranging from
asymptomatic infection to life threatening severe disease. Host microRNAs have been …

Circulating microRNA profiles predict the severity of COVID-19 in hospitalized patients

D De Gonzalo-Calvo, ID Benitez, L Pinilla… - Translational …, 2021 - Elsevier
We aimed to examine the circulating microRNA (miRNA) profile of hospitalized COVID-19
patients and evaluate its potential as a source of biomarkers for the management of the …

Circulating miR-320b and miR-483-5p levels are associated with COVID-19 in-hospital mortality

A Giuliani, G Matacchione, D Ramini, M Di Rosa… - Mechanisms of Ageing …, 2022 - Elsevier
The stratification of mortality risk in COVID-19 patients remains extremely challenging for
physicians, especially in older patients. Innovative minimally invasive molecular biomarkers …

[HTML][HTML] Altered microRNA expression in COVID-19 patients enables identification of SARS-CoV-2 infection

RJ Farr, CL Rootes, LC Rowntree, THO Nguyen… - PLoS …, 2021 - journals.plos.org
The host response to SARS-CoV-2 infection provide insights into both viral pathogenesis
and patient management. The host-encoded microRNA (miRNA) response to SARS-CoV-2 …

Cellular miR-150-5p may have a crucial role to play in the biology of SARS-CoV-2 infection by regulating nsp10 gene

SM Akula, P Bolin, PP Cook - RNA biology, 2022 - Taylor & Francis
The role for circulating miRNAs as biomarkers of the COVID-19 disease remains uncertain.
We analysed the circulating miRNA profile in twelve COVID-19 patients with moderate …

Circulating miRNAs: Potential diagnostic role for coronavirus disease 2019 (COVID-19)

M Fayyad-Kazan, R Makki, N Skafi, M El Homsi… - Infection, Genetics and …, 2021 - Elsevier
Nowadays, the coronavirus disease (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) represents a major global health …

[HTML][HTML] MicroRNAs and cytokines as potential predictive biomarkers for COVID-19 disease progression

HA Mohamed, AE Abdelkafy, RMM Khairy… - Scientific reports, 2023 - nature.com
Host microRNAs can influence the cytokine storm associated SARS-CoV-2 infection and
proposed as biomarkers for COVID-19 disease. In the present study, serum MiRNA-106a …

[HTML][HTML] Circulating microRNA profiling is altered in the acute respiratory distress syndrome related to SARS-CoV-2 infection

N Garcia-Giralt, J Du, J Marin-Corral… - Scientific Reports, 2022 - nature.com
One of the hallmarks of SARS-CoV-2 infection is an induced immune dysregulation, in some
cases resulting in cytokine storm syndrome and acute respiratory distress syndrome …

What is the potential function of microRNAs as biomarkers and therapeutic targets in COVID-19?

A Guterres, CH de Azeredo Lima, RL Miranda… - Infection, genetics and …, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of COVID-19,
a pandemic associated with substantial morbidity and mortality. Despite of this, no vaccine …