Background Cardiotoxicity is a major complication of anticancer drugs, including
anthracyclines and 5-fluorouracil (5-FU) and it can have detrimental effects both in patients …

Fluoropyrimidines are key agents for the treatment of gastrointestinal tract
adenocarcinomas. The possible cardiotoxic effects in patients and occupationally exposed …

Antimetabolites are a class of effective anticancer drugs interfering in essential biochemical
processes. 5-Fluorouracil (5-FU) and its prodrug Capecitabine are widely used in the …

5-Fluorouracil (5-FU) and its prodrug capecitabine are key chemotherapeutic agents in the
treatment of many gastrointestinal tract adenocarcinomas. In addition to their beneficial …

Tumors and heart disease are two of the leading causes of human death. With the
development of anti-cancer therapy, the survival rate of cancer patients has been …

Doxorubicin is useful anticancer drug because it's used in treatment of acute leukemia,
Hodgkin's and non-Hodgkin's lymphomas, and many other malignant neoplasm. The …

Background and Objective. 5‐Fluorouracil is one of the most common chemotherapeutic
agents used in the treatment of solid tumors. 5‐Fluorouracil‐associated cardiotoxicity is the …

Chemotherapy‐induced cardiotoxicity is a serious complication that poses a serious threat
to life and limits the clinical use of various chemotherapeutic agents, particularly the …

As medicine advances to employ sophisticated anticancer agents to treat a vast array of
oncological conditions, it is worth considering side effects associated with several …

Background Cardiotoxicity is a serious side effect to treatment with 5-fluorouracil (5-FU), but
the underlying mechanisms are not fully understood. The objective of this systematic review …