Macrophage inflammatory protein‐1α in term and preterm parturtition: Effect of microbial invasion of the amniotic cavity

R Romero, R Gomez, M Galasso… - American Journal of …, 1994 - Wiley Online Library
PROBLEM: This study was conducted to determine whether:(1) gestational age, parturition,
and microbial invasion of the amniotic cavity (MIAC) are associated with changes in amniotic …

Elevations of amniotic fluid macrophage inflammatory protein-1α concentrations in women during term and preterm labor

DJ Dudley, C Hunter, MD Mitchell, MW Varner - Obstetrics & Gynecology, 1996 - Elsevier
OBJECTIVE: To determine whether elevated concentrations of macrophage inflammatory
protein-1α (MIP-la) in amniotic fluid (AF) are related to term and preterm labor. METHODS …

The value of amniotic fluid interleukin‐6, white blood cell count, and gram stain in the diagnosis of microbial invasion of the amniotic cavity in patients at term

R Gomez, R Romero, M Galasso… - American journal of …, 1994 - Wiley Online Library
PROBLEM: Subclinical microbial invasion of the amniotic cavity occurs in 18.8% of women
with term labor and intact membranes and in 34% of patients with term PROM and is a risk …

Interleukin‐1α and Interleukin‐1 β in Preterm and Term Human Parturition

R ROMERO, M MAZOR, F BRANDT… - American journal of …, 1992 - Wiley Online Library
Interleukin‐1 (IL‐1) has been implicated in the mechanism of human parturition in the setting
of infection. The purpose of this study was to determine the effect of labor (term and preterm) …

Amniotic fluid interleukin-6 levels correlate with histologic chorioamnionitis and amniotic fluid cultures in patients in premature labor with intact membranes

PC Greig, JM Ernest, L Teot, M Erikson… - American journal of …, 1993 - Elsevier
Objective: Our purpose was (1) to determine the frequency of intraamniotic and
extraamniotic intrauterine infection in patients with premature labor and intact membranes …

Cellular immune responses in amniotic fluid of women with preterm labor and intra‐amniotic infection or intra‐amniotic inflammation

N Gomez‐Lopez, R Romero, J Galaz… - American Journal of …, 2019 - Wiley Online Library
Problem Preterm birth is commonly preceded by preterm labor, a syndrome that is causally
linked to both intra‐amniotic infection and intra‐amniotic inflammation. However, the …

Regulation of human decidual cell macrophage inflammatory protein‐1α (MIP‐1α) production by inflammatory cytokines

DJ Dudley, S Spencer, S Edwin… - American Journal of …, 1995 - Wiley Online Library
PROBLEM: Inflammation of human gestational tissues is a key pathophysiologic event in the
genesis of infection‐associated preterm labor. Human gestational tissues produce several …

Midtrimester amniotic fluid concentrations of interleukin-6 and interferon-gamma-inducible protein-10: evidence for heterogeneity of intra-amniotic inflammation and …

MT Gervasi, R Romero, G Bracalente… - Journal of perinatal …, 2012 - degruyter.com
Introduction: Intra-amniotic inflammation is traditionally defined as an elevation of amniotic
fluid interleukin (IL)-6. Previous case control studies have suggested an association …

Evaluation of amniotic fluid cytokines in preterm labor and intact membranes

R Figueroa, D Garry, A Elimian, K Patel… - The Journal of …, 2005 - Taylor & Francis
Objective. To compare the amniotic fluid (AF) concentration of pro-inflammatory cytokines
between women with preterm labor and intact membranes that delivered within 7 days, with …

Clinical significance of intra-amniotic inflammation in patients with preterm labor and intact membranes

BH Yoon, R Romero, JB Moon, SS Shim, M Kim… - American journal of …, 2001 - Elsevier
Objective: The purpose of this study was to determine the frequency and clinical significance
of intraamniotic inflammation in patients with preterm labor and intact membranes. Study …