Background Alzheimer's disease (AD) is the most common form of dementia, characterized
by progressive cognitive impairment and neurodegeneration. However, despite extensive …

Abstract Background Transcriptional studies suggest Alzheimer's disease (AD) involves
dysfunction of many cellular pathways, including synaptic transmission, cytoskeletal …

Alzheimer's disease (AD) is a devastating neurological disorder characterized by changes in
cell-type proportions and consequently marked alterations of the transcriptome. Here we use …

Here, we report proteomic analyses of 129 human cortical tissues to define changes
associated with the asymptomatic and symptomatic stages of Alzheimer's disease (AD) …

Alzheimer's disease (AD) is a heterogeneous disorder with abnormalities in multiple
biological domains. In an advanced machine learning analysis of postmortem brain and in …

Alzheimer's disease (AD), the most common form of dementia, is recognized as a
heterogeneous disease with diverse pathophysiologic mechanisms. In this study, we …

Over 25 genes are known to affect the risk of developing Alzheimer disease (AD), the most
common neurodegenerative dementia. However, mechanistic insights and improved …

There is a need for new therapeutic targets with which to prevent Alzheimer's disease (AD),
a major contributor to aging-related cognitive decline. Here we report the construction and …

Alzheimer's Disease (AD) is the most widespread form of dementia during the later stages of
life. If improved therapeutics are not developed, the prevalence of AD will drastically …

Alzheimer's disease is the most common neurological disease worldwide. Unfortunately,
there are currently no effective treatment methods nor early detection methods. Furthermore …