Identification of differentially expressed genes and key pathways in the dorsal root ganglion after chronic compression

Z Du, S Yin, X Song, L Zhang, S Yue, X Jia… - Frontiers in Molecular …, 2020 - frontiersin.org
Neuropathic pain (NP) is caused by primary or secondary impairment of the peripheral or
central nervous systems. Its etiology is complex and involves abnormal patterns of gene …

A transcriptomic analysis of neuropathic pain in rat dorsal root ganglia following peripheral nerve injury

W Sun, D Kou, Z Yu, S Yang, C Jiang, D Xiong… - Neuromolecular …, 2020 - Springer
The aim of this work is to provide a comprehensive and unbiased understanding at the
molecular correlates of peripheral nerve injury. In this study, we screened the differentially …

Identification of key genes and pathways associated with neuropathic pain in uninjured dorsal root ganglion by using bioinformatic analysis

CJ Chen, DZ Liu, WF Yao, Y Gu, F Huang… - Journal of pain …, 2017 - Taylor & Francis
Purpose Neuropathic pain is a complex chronic condition occurring post-nervous system
damage. The transcriptional reprogramming of injured dorsal root ganglia (DRGs) drives …

Analyses of gene expression profiles in the rat dorsal horn of the spinal cord using RNA sequencing in chronic constriction injury rats

H Du, J Shi, M Wang, S An, X Guo, Z Wang - Journal of neuroinflammation, 2018 - Springer
Background Neuropathic pain is caused by damage to the nervous system, resulting in
aberrant pain, which is associated with gene expression changes in the sensory pathway …

Weighted gene co-expression network analysis reveals specific modules and hub genes related to neuropathic pain in dorsal root ganglions

N Cheng, Z Zhang, Y Guo, ZL Qiu, JY Du… - Bioscience …, 2019 - portlandpress.com
Neuropathic pain is a common, debilitating clinical issue. Here, the weighted gene co-
expression network analysis (WGCNA) was used to identify the specific modules and hub …

Neuroinflammation signatures in dorsal root ganglia following chronic constriction injury

Y Qu, R Cai, Q Li, H Wang, L Lu - Heliyon, 2024 - cell.com
Neuropathic pain (NP) is a common debilitating chronic pain condition with limited effective
therapeutics. Further investigating mechanisms underlying NP is therefore of great …

The Wnt/β‐Catenin Pathway Regulated Cytokines for Pathological Neuropathic Pain in Chronic Compression of Dorsal Root Ganglion Model

Y Zhang, D Zhao, X Li, B Gao, C Sun, S Zhou… - Neural …, 2021 - Wiley Online Library
Neuropathic pain is one of the important challenges in the clinic. Although a lot of research
has been done on neuropathic pain (NP), the molecular mechanism is still elusive. We …

[HTML][HTML] Time-Course Progression of Whole Transcriptome Expression Changes of Trigeminal Ganglia Compared to Dorsal Root Ganglia in Rats Exposed to Nerve …

OA Korczeniewska, S Husain, M Hoque… - The Journal of …, 2024 - Elsevier
Mechanisms underlying neuropathic pain (NP) are complex with multiple genes, their
interactions, environmental and epigenetic factors being implicated. Transcriptional changes …

[HTML][HTML] Effect of surgical damage to spinal nerve on dorsal-root ganglion gene expressions: Comprehensive analysis of differentially expressed genes

C Xu, TY Liu, YP Zhang, Y Feng - Asian Journal of Surgery, 2022 - Elsevier
Background Neuropathic pain can cause significant physical and economic burden, and
there are no effective long-term treatments. We conducted a bioinformatics analysis to …

Identification of key genes and pathways in mouse spinal cord involved in ddC-induced neuropathic pain by transcriptome sequencing

S Wu, S Yang, CB Bloe, R Zhuang, J Huang… - Journal of Molecular …, 2021 - Springer
Highly active antiretroviral therapy (HAART) works effectively in inhibiting HIV replication in
patients. However, the use of nucleoside reverse transcriptase inhibitors (NRTIs) often …