mRNA-1273 vaccine induces neutralizing antibodies against spike mutants from global SARS-CoV-2 variants

K Wu, AP Werner, JI Moliva, M Koch, A Choi… - BioRxiv, 2021 - biorxiv.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causative infection of
a global pandemic that has led to more than 2 million deaths worldwide. The Moderna …

[HTML][HTML] SARS-CoV-2 variant B. 1.1. 7 is susceptible to neutralizing antibodies elicited by ancestral spike vaccines

X Shen, H Tang, C McDanal, K Wagh, W Fischer… - Cell host & …, 2021 - cell.com
All current vaccines for COVID-19 utilize ancestral SARS-CoV-2 spike with the goal of
generating protective neutralizing antibodies. The recent emergence and rapid spread of …

Preliminary analysis of safety and immunogenicity of a SARS-CoV-2 variant vaccine booster

K Wu, A Choi, M Koch, LZ Ma, A Hill, N Nunna… - MedRxiv, 2021 - medrxiv.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of a
global pandemic of coronavirus disease 2019 (COVID-19) that has led to more than 3 …

[HTML][HTML] The E484K mutation in the SARS-CoV-2 spike protein reduces but does not abolish neutralizing activity of human convalescent and post-vaccination sera.

S Jangra, C Ye, R Rathnasinghe, D Stadlbauer… - MedRxiv, 2021 - ncbi.nlm.nih.gov
One year in the coronavirus disease 2019 (COVID-19) pandemic, the first vaccines are
being rolled out under emergency use authorizations. It is of great concern that newly …

Neutralizing antibodies to SARS‐CoV‐2 variants of concern including Delta and Omicron in subjects receiving mRNA‐1273, BNT162b2, and Ad26. COV2. S vaccines

GF Zhang, W Meng, L Chen, L Ding… - Journal of Medical …, 2022 - Wiley Online Library
SARS‐CoV‐2 vaccines have contributed to the control of COVID‐19 in some parts of the
world. However, the constant emergence of variants of concern (VOCs) challenges the …

[HTML][HTML] SARS-CoV-2 spike variants exhibit differential infectivity and neutralization resistance to convalescent or post-vaccination sera

A Kuzmina, Y Khalaila, O Voloshin, A Keren-Naus… - Cell host & …, 2021 - cell.com
Toward eradicating the COVID-19 pandemic, vaccines that induce high humoral and cellular
immune responses are essential. However, SARS-CoV-2 variants have begun to emerge …

[HTML][HTML] Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity

WF Garcia-Beltran, EC Lam, KS Denis, AD Nitido… - Cell, 2021 - cell.com
Vaccination elicits immune responses capable of potently neutralizing SARS-CoV-2.
However, ongoing surveillance has revealed the emergence of variants harboring mutations …

Neutralization of viruses with European, South African, and United States SARS-CoV-2 variant spike proteins by convalescent sera and BNT162b2 mRNA vaccine …

T Tada, BM Dcosta, M Samanovic-Golden, RS Herati… - BioRxiv, 2021 - biorxiv.org
The increasing prevalence of SARS-CoV-2 variants with mutations in the spike protein has
raised concerns that recovered individuals may not be protected from reinfection and that …

[HTML][HTML] SARS-CoV-2 variants show resistance to neutralization by many monoclonal and serum-derived polyclonal antibodies

M Diamond, R Chen, X Xie, J Case, X Zhang… - Research …, 2021 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the global
COVID-19 pandemic infecting more than 106 million people and causing 2.3 million deaths …

Neutralization of SARS-CoV-2 variants by convalescent and BNT162b2 vaccinated serum

TA Bates, HC Leier, ZL Lyski, SK McBride… - Nature …, 2021 - nature.com
SARS-CoV-2 and its variants continue to infect hundreds of thousands every day despite the
rollout of effective vaccines. Therefore, it is essential to understand the levels of protection …