Adenovirus type 5 SARS-CoV-2 vaccines delivered orally or intranasally reduced disease severity and transmission in a hamster model
SN Langel, S Johnson, CI Martinez… - Science Translational …, 2022 - science.org
Transmission-blocking strategies that slow the spread of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and protect against coronavirus disease 2019 (COVID-19) are …
coronavirus 2 (SARS-CoV-2) and protect against coronavirus disease 2019 (COVID-19) are …
Next generation mucosal vaccine strategy for respiratory pathogens
F Dotiwala, AK Upadhyay - Vaccines, 2023 - mdpi.com
Inducing humoral and cytotoxic mucosal immunity at the sites of pathogen entry has the
potential to prevent the infection from getting established. This is different from systemic …
potential to prevent the infection from getting established. This is different from systemic …
A single dose of an adenovirus-vectored vaccine provides protection against SARS-CoV-2 challenge
S Wu, G Zhong, J Zhang, L Shuai, Z Zhang… - Nature …, 2020 - nature.com
The unprecedented coronavirus disease 2019 (COVID-19) epidemic has created a
worldwide public health emergency, and there is an urgent need to develop an effective …
worldwide public health emergency, and there is an urgent need to develop an effective …
[PDF][PDF] Single-dose intranasal administration of AdCOVID elicits systemic and mucosal immunity against SARS-CoV-2 and fully protects mice from lethal challenge …
RG King, A Silva-Sanchez, JN Peel, D Botta… - DOI: https://doi. org …, 2021 - academia.edu
The coronavirus disease 2019 (COVID-19) pandemic has highlighted the urgent need for
effective prophylactic vaccination to prevent the spread of severe acute respiratory …
effective prophylactic vaccination to prevent the spread of severe acute respiratory …
Single-dose intranasal administration of AdCOVID elicits systemic and mucosal immunity against SARS-CoV-2 and fully protects mice from lethal challenge
RG King, A Silva-Sanchez, JN Peel, D Botta… - Vaccines, 2021 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic has highlighted the urgent need for
effective prophylactic vaccination to prevent the spread of severe acute respiratory …
effective prophylactic vaccination to prevent the spread of severe acute respiratory …
Adenoviral vector-based vaccine platform for COVID-19: Current status
The coronavirus disease (COVID-19) breakout had an unimaginable worldwide effect in the
21st century, claiming millions of lives and putting a huge burden on the global economy …
21st century, claiming millions of lives and putting a huge burden on the global economy …
Mucosal vaccines for SARS-CoV-2: triumph of hope over experience
D Pilapitiya, AK Wheatley, HX Tan - EBioMedicine, 2023 - thelancet.com
Currently approved COVID-19 vaccines administered parenterally induce robust systemic
humoral and cellular responses. While highly effective against severe disease, there is …
humoral and cellular responses. While highly effective against severe disease, there is …
Adenoviral vector‐based platforms for developing effective vaccines to combat respiratory viral infections
A Elkashif, M Alhashimi… - Clinical & …, 2021 - Wiley Online Library
Since the development of the first vaccine against smallpox over two centuries ago,
vaccination strategies have been at the forefront of significantly impacting the incidences of …
vaccination strategies have been at the forefront of significantly impacting the incidences of …
Safety, mucosal and systemic immunopotency of an aerosolized adenovirus-vectored vaccine against SARS-CoV-2 in rhesus macaques
F Xu, S Wu, L Yi, S Peng, F Wang, W Si… - Emerging microbes & …, 2022 - Taylor & Francis
Mucosal immunity provides a potential for preventing initial infection and stopping
subsequent transmission of SARS-CoV-2. Here, we examined the safety and …
subsequent transmission of SARS-CoV-2. Here, we examined the safety and …