Current advances in the treatment of Parkinson's disease with stem cells

KA Trzaska, P Rameshwar - Current Neurovascular Research, 2007 - ingentaconnect.com
Stem cell replacement has emerged as the novel therapeutic strategy for Parkinson's
disease (PD). Control of motor behavior is lost in PD due to the selective degeneration of …

Stem cell therapy for Parkinson's disease

J Takahashi - Expert Review of Neurotherapeutics, 2007 - Taylor & Francis
The aim of stem cell therapy for Parkinson's disease is to reconstruct nigro–striatal neuronal
pathways using endogenous neural stem/precursor cells or grafted dopaminergic neurons …

[HTML][HTML] Current status and future perspectives on stem cell-based therapies for Parkinson's disease

Y Cha, TY Park, P Leblanc, KS Kim - Journal of Movement …, 2023 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is the second most common neurodegenerative disorder after
Alzheimer's disease, affecting 1%–2% of the population over the age of 65. As the …

Stem cells may reshape the prospect of Parkinson's disease therapy

KC Sonntag, R Simantov, O Isacson - Molecular Brain Research, 2005 - Elsevier
The concept of cell replacement to compensate for cell loss and restore functionality has
entered several disease entities including neurodegenerative disorders. Recent clinical …

Stem cell therapy for Parkinson's disease: where do we stand?

L Roybon, NS Christophersen, P Brundin, JY Li - Cell and tissue research, 2004 - Springer
A major neuropathological feature of Parkinson's disease (PD) is the loss of nigrostriatal
dopaminergic neuron. Patients exhibit motor symptoms, including bradykinesia, rigidity, and …

Stem cell‐based therapy for Parkinson's disease

AS Correia, SV Anisimov, JY Li, P Brundin - Annals of Medicine, 2005 - Taylor & Francis
Motor dysfunctions in Parkinson's disease are considered to be primarily due to the
degeneration of dopaminergic neurons in the substantia nigra pars compacta …

Stem cells and Parkinson's disease: toward a treatment, not a cure

C Svendsen - Cell Stem Cell, 2008 - cell.com
Early clinical trials designed to treat Parkinson's disease by transplantation of fetal tissue
containing dopamine neuron precursors yielded promising results, but the approach retains …

[HTML][HTML] Recent advances in cell-based therapy for Parkinson disease

A Astradsson, O Cooper, A Vinuela, O Isacson - Neurosurgical Focus, 2008 - thejns.org
✓ In this review, the authors discuss recent advances in the field of cell therapy for Parkinson
disease (PD). They compare and contrast recent clinical trials using fetal dopaminergic …

Cell-based therapeutic approaches for Parkinson's disease: progress and perspectives

SV Anisimov - Reviews in the Neurosciences, 2009 - degruyter.com
Motor djsfunctions in Parkinson's disease a· e believed to be primarily due to the
degeneration of dopamincrgic neurons located in the substantia nigra pars compacta …

Towards stem cell replacement therapies for Parkinson's disease

E Arenas - Biochemical and biophysical research communications, 2010 - Elsevier
Current therapeutic approaches for Parkinson's disease (PD) provide symptomatic relief but
none of them change the course of disease. There is therefore a clear need for regenerative …