Background Our objective was to study omeprazole as a single‐dose oral probe in the
determination of CYP2C19 phenotype in black subjects and to determine the correlation …

The objective of this study was to determine the reliability of omeprazole as a marker for
CYP2C19 activity in Chinese subjects. In 27 healthy male Chinese subjects, the CYP2C19 …

Omeprazole has been used as a drug probe for CYP2C19, but no systematic data are
available for Mexican populations. The aim of this study was to evaluate the phenotype …

Objectives To identify defective alleles of CYP2C19 (CYP2C19* 2 and* 3) in North Indians.
Methods One hundred extensive metabolizers and 21 poor metabolizers of omeprazole …

Omeprazole (20 mg orally) was given to 103 healthy Korean subjects and blood was taken 3
h alter administration. The plasma concentration ratio of omeprazole and …

Aims To evaluate the reliability of the omeprazole hydroxylation index as a marker for
polymorphic CYP2C19 activity in a Japanese population of healthy young subjects (n= 78) …

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT• The only existing study of CYP2C19*
17‐associated alterations in drug pharmacokinetics was retrospective and compared probe …

To investigate the relationship between CYP2C19 genotypes and the hydroxylation index
(HI) of omeprazole in the South Indian population. Healthy unrelated South Indian subjects …

Background Literature addressing the effect of sex on cytochrome P450 (CYP) 2C19 activity
is conflicting. The exogenous female sex steroid hormones used in oral contraceptives are …

The pharmacokinetic profile of omeprazole was examined in 27 healthy Japanese
volunteers, and the results were analyzed in relation to genotype for the two mutations …