LA Stevens, AS Levey - Clinical Pharmacology & Therapeutics, 2009 - Wiley Online Library
Clinical laboratories now use standardized serum creatinine assays and the Modification of Diet in Renal Disease (MDRD) study equation to report estimated glomerular filtration rate …
International guidelines recommend the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) method to monitor kidney function in chronic kidney disease using …
BACKGROUND: Kidney disease alters the pharmacokinetic disposition of many medications, requiring dosage adjustment to maintain therapeutic serum concentrations …
Accurate assessment of kidney function is an important component of determining appropriate medication dosing regimens. Nearly all manufacturer-recommended dose …
CL Smith, EM Hampton - DICP, 1990 - journals.sagepub.com
Estimates of renal function are frequently used to design individual dosing regimens. The accuracy of these estimates naturally influences their ability to predict certain …
Creatinine clearance has been the most common method of estimating kidney function for the purpose of drug dosing for decades. The availability and extensive clinical use of …
In 2002, the Kidney Disease Outcomes Quality Initiative recommended the use of an estimated glomerular filtration rate (eGFR) to detect early kidney disease (1). Subsequently …
Accurate assessment of kidney function is an important component of determining appropriate drug dosing regimens. Nearly all manufacturer‐recommended dosage …
V Schneider, V Henschel… - Clinical …, 2003 - Wiley Online Library
Background Doses of renally eliminated drugs should be adjusted according to kidney function to prevent adverse drug events and cost. Dose adjustment can be based on serum …