Alterations in the levels of dehydroepiandrosterone (DHEA) in the brain can allosterically
modulate γ-aminobutyric-acid-type-A (GABA AR), N-methyl-D-aspartate (NMDAR), and …

We aimed to verify whether DHEA, a neuoroactive neurosteroid, has a protective role in
preventing the occurrence or enhancement of the severity of depression and anxiety in mice …

Dehydroepiandrosterone (DHEA) and its sulfate ester, DHEAS, exert multiple effects in the
rodent central nervous system (CNS). Most of them seem to be mediated through their non …

Dehydroepiandrosterone (DHEA) and its metabolites, DHEA-sulphate (DHEA-S) and
androsterone, have neurosteroid activity. In this study, we examined whether DHEA, DHEA …

Objective The pathophysiology of major depressive disorder (MDD) is still not well
understood. Conflicting results for surrogate biomarkers in MDD have been reported, which …

Dehydroepiandrosterone (DHEA) exerts multiple effects in the rodent central nervous
system (CNS), mediated through its nongenomic actions on several neurotransmitter …

It has been shown that the steroid dehydroepiandrosterone (DHEA) interacts with dopamine
(DA) and serotonin (5-HT) neurotransmitter systems, which are involved in the …

Various studies reported beneficial effects of dehydroepiandrosterone (DHEA) and its
sulphate (DHEAS), the neurosteroids involved in various brain functions, on synaptic …

Background Dehydroepiandrosterone (DHEA) and its sulfated ester DHEA-sulfate (DHEA-
S),(together DHEA [S]), are the most abundant adrenal steroids in humans and are found in …

Dehydroepiandrosterone (DHEA) is a neurosteroid with anxiolytic, antidepressant, and
antiglucocorticoid properties. It is endogenously released in response to stress, and may …