What are the effects of our environment on human development and the next generation? Numerous studies have provided ample evidence that a healthy environment and lifestyle of …
The use of non-human animals in research is a longstanding practice to help us understand and improve human biology and health. Animal models allow researchers, for example, to …
Epidemiological evidence increasingly suggests that environmental exposures early in development have a role in susceptibility to disease in later life. In addition, some of these …
DC Dolinoy, JR Weidman, RL Jirtle - Reproductive toxicology, 2007 - Elsevier
Traditional studies on the combined effects of genetics and the environment on individual variation in disease susceptibility primarily focus on single nucleotide polymorphisms that …
AJ Drake, L Liu - Trends in Endocrinology & Metabolism, 2010 - cell.com
Epidemiological studies have shown that the environment experienced in early life can 'programme'susceptibility to later disease. Furthermore, there is increasing evidence that …
Though there are multiple routes through which parents can influence their offspring, recent studies of environmentally induced epigenetic variation have highlighted the role of non …
The environment can have a long‐lasting influence on an individual's physiology and behavior. While some environmental conditions can be beneficial and result in adaptive …
The epigenome is the overall epigenetic state of a cell and represents the ensemble of chromatin modifications. It is an essential mechanism for the regulation of the genome that …
A Vaiserman - Clinical epigenetics, 2015 - Springer
A growing body of evidence suggests that the risk of development and progression of a variety of human chronic diseases depends on epigenetic modifications triggered by …