The severe acute respiratory syndrome (SARS) has been one of the most epidemic
diseases threatening human health all over the world. Based on clinical studies, SARS-CoV …

Two candidate small interfering RNAs (siRNAs) corresponding to severe acute respiratory
syndrome-associated coronavirus (SARS-CoV) spike gene were designed and in vitro …

Serious outbreaks of severe acute respiratory syndrome (SARS), caused by the newly
discovered coronavirus SARS-CoV, occurred between late 2002 and early 2003 and there …

Abstract SARS-CoV (the SARS-Associated Coronavirus) was reported as a novel virus
member in the coronavirus family, which was the cause of severe acute respiratory …

The severe acute respiratory syndrome coronavirus (SARS CoV) genome has 14 potential
open reading frames (ORFs). The first ORF is translated from the full-length genomic mRNA …

Methods We designed six 21-mer SARSis (siRNAs [GENSET SA Ltd, Paris, France]
targeting different sites of the replicase 1A region of the SARS coronavirus [SARS-CoV] …

ABSTRACT RNA interference (RNAi) is triggered by the presence of a double-stranded RNA
(dsRNA), and results in the silencing of homologous gene expression through the specific …

Until the appearance of severe acute respiratory syndrome (SARS), caused by the SARS
coronavirus (SARS-CoV) in early 2003, coronavirus infection was not considered to be …

Severe acute respiratory syndrome (SARS) is an acute respiratory infectious disease that
spread worldwide in early 2003. The cause was determined as a novel coronavirus (CoV) …

Severe acute respiratory syndrome (SARS) is a highly contagious and sometimes a lethal
disease, which spread over five continents in 2002–2003. Laboratory analysis showed that …