CR Goodlett, KH Horn, FC Zhou - Experimental biology and …, 2005 - journals.sagepub.com
There are multiple mechanisms by which alcohol can damage the developing brain, but the type of damage induced will depend on the amount and developmental timing of exposure …
Fetal alcohol exposure has multiple deleterious effects on brain development, and represents a leading known cause of mental retardation. This review of the effects of alcohol …
JR West, CR Goodlett - Annals of medicine, 1990 - Taylor & Francis
There is convincing evidence that alcohol is teratogenic both in humans and animals and that its most devastating effects are on the developing brain. However, much information is …
The ingestion of alcohol/ethanol during pregnancy can result in abnormal fetal development in both humans and a variety of experimental animal models. Depending on the pattern of …
SM Smith - Alcohol health and research world, 1997 - ncbi.nlm.nih.gov
Exposure to alcohol during gestation can have profound consequences, but not all cells within the embryo are affected equally. Recent advances in molecular embryology have …
C Guerri - Neurotoxicity research, 2002 - Springer
Clinical and experimental evidence has demonstrated that ethanol is a teratogen, and that its consumption during pregnancy induces harmful effects on the developing foetus that …
KL Jones - Birth Defects Research Part C: Embryo Today …, 2011 - Wiley Online Library
Prenatal exposure to alcohol has profound effects on many aspects of fetal development. Although alterations of somatic growth and specific minor malformations of facial structure …
JH Hannigan - Pharmacology Biochemistry and Behavior, 1996 - Elsevier
The substantial advances in understanding fetal alcohol syndrome over the past 20 years were made in large part because of research with animals. This review illustrates recent …
JR West, CR Goodlett, DJ Bonthius… - Alcoholism: Clinical …, 1990 - Wiley Online Library
Neuronal death is one of the most serious consequences of alcohol exposure during development. Studies described in this paper used a neonatal rat model to address factors …