[HTML][HTML] Mechanisms of alcohol-induced damage to the developing nervous system

CR Goodlett, KH Horn - Alcohol Research & Health, 2001 - ncbi.nlm.nih.gov
Numerous mechanisms likely contribute to the damaging effects of prenatal alcohol
exposure on the developing fetus and particularly the developing central nervous system …

Alcohol teratogenesis: mechanisms of damage and strategies for intervention

CR Goodlett, KH Horn, FC Zhou - Experimental biology and …, 2005 - journals.sagepub.com
There are multiple mechanisms by which alcohol can damage the developing brain, but the
type of damage induced will depend on the amount and developmental timing of exposure …

Fetal alcohol syndrome: the vulnerability of the developing brain and possible mechanisms of damage

JR West, WJA Chen, NJ Pantazis - Metabolic brain disease, 1994 - Springer
Fetal alcohol exposure has multiple deleterious effects on brain development, and
represents a leading known cause of mental retardation. This review of the effects of alcohol …

Teratogenic effects of alcohol on brain development

JR West, CR Goodlett - Annals of medicine, 1990 - Taylor & Francis
There is convincing evidence that alcohol is teratogenic both in humans and animals and
that its most devastating effects are on the developing brain. However, much information is …

The role of oxidative stress in fetal alcohol spectrum disorders

PS Brocardo, J Gil-Mohapel, BR Christie - Brain research reviews, 2011 - Elsevier
The ingestion of alcohol/ethanol during pregnancy can result in abnormal fetal development
in both humans and a variety of experimental animal models. Depending on the pattern of …

[HTML][HTML] Alcohol-induced cell death in the embryo

SM Smith - Alcohol health and research world, 1997 - ncbi.nlm.nih.gov
Exposure to alcohol during gestation can have profound consequences, but not all cells
within the embryo are affected equally. Recent advances in molecular embryology have …

Mechanisms involved in central nervous system dysfunctions induced by prenatal ethanol exposure

C Guerri - Neurotoxicity research, 2002 - Springer
Clinical and experimental evidence has demonstrated that ethanol is a teratogen, and that
its consumption during pregnancy induces harmful effects on the developing foetus that …

The effects of alcohol on fetal development

KL Jones - Birth Defects Research Part C: Embryo Today …, 2011 - Wiley Online Library
Prenatal exposure to alcohol has profound effects on many aspects of fetal development.
Although alterations of somatic growth and specific minor malformations of facial structure …

What research with animals is telling us about alcohol-related neurodevelopmental disorder

JH Hannigan - Pharmacology Biochemistry and Behavior, 1996 - Elsevier
The substantial advances in understanding fetal alcohol syndrome over the past 20 years
were made in large part because of research with animals. This review illustrates recent …

Cell population depletion associated with fetal alcohol brain damage: mechanisms of BAC‐dependent cell loss

JR West, CR Goodlett, DJ Bonthius… - Alcoholism: Clinical …, 1990 - Wiley Online Library
Neuronal death is one of the most serious consequences of alcohol exposure during
development. Studies described in this paper used a neonatal rat model to address factors …